(I haven't read the paper yet.) All the participants went to the test centre for a test, so they were either having symptoms of some sort or there...
Yes, but this study seems to suggest that there is a different sort of damage, that requires a specific sort of scanning. I don't think we are...
Googling, it seems that light sensitivity is common in MS. It is thought that demyelination affects the function of the optic nerve, making the...
We've talked before how researchers need to pay more attention to non-CPET exertion during PEM studies. It might be that participants need to...
Yes, exactly @Peter Trewhitt. Well said.
[ATTACH] [ATTACH] I agree. It looks like a blob, there's not much action implicit in that. It's also high contrast and the words are jammed up...
Yes, it's not clear if the editorial notes are supposed to be a record of what happened (in which case, each Editorial Note would be left as it...
My reasons for thinking the note is an improvement is that it is very clear, with little to distract from the statement that the review was...
My ideal note would be something like: "This Cochrane review was published in 2019 though we knew it was rubbish even then. The studies it...
That's an improvement to the editorial note. I wonder why Cochrane didn't put a new publication date on the review, making it a 2025 review...
IACFS/ME are asking if their conference should be virtual. There's also a space to make a comment about what the conference. I took the...
Czech guideline for GPs: Functional and persistent somatic symptoms: Psychosomatic approach, 2023
Any news @Joan Crawford?
Well, yes. But it is even worse than that. J-A: Exercise vs leaflet J-A: Exercise vs leaflet Li: Telerehab vs brief instructions at baseline...
Perhaps relevant: Reversible reduction in brain myelin content upon marathon running, 2025, Ramos-Cabrer et al.
It's interesting to read this paper: Inactivation of ATG13 stimulates chronic demyelinating pathologies in muscle‑serving nerves and spinal cord,...
Also, this phenomenon doesn't necessarily have to explain PEM, or at least PEM in its entirety. If this is downstream of an inability to use...
Thanks for the information and the link to the forum thread SNT. So, that's sounding pretty interesting as a technique to apply to ME/CFS then?
That's interesting. They consider the possibility that dehydration is causing the change in MWF, but they seem confident that it isn't. They...
Yes, Cochrane (at least here) is correctly clear that an absence of blinding among the participants does not necessarily make an intervention...
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