That’s very possible. And Negative findings are hard to publish in any field. But I would like to see a better version of this study done that...
Do you have any indication of how this group’s severity compares with people who took part in the Pace trial? The six minute walking test worked...
Thanks for pointing that out. As I said, I only skimmed. So, they calculated the right measure, and highlighted wrong ones that looked better? I...
I’ve only had the energy to skim the thread and the paper, so this might be a little off track, or repeating what’s already been said. But I...
It is, thank you. I think I understand the key metabolic ideas more clearly. Though presumably the central question for any theory to answer is,...
Thanks. I was hoping for something more succinct because of my brain fog. From a quick scan of your other post, malate seems to play a central...
Thanks. Presumably, there are vast numbers of possibilities as to what has gone wrong in ME/CFS (I've been reading research papers for 30 years...
I'm not sure we have robust data on asymptomatic infections causing LC, given the very broad definition of LC and whether asymptomatic infections...
@Jonathan Edwards mentioned that mental exertion uses little extra energy, so it probably doesn't fit with thinking triggering PEM through simple...
I think a common experience is that PEM feels the same where it was triggered by physical or mental exertion. I guess one possibility is its...
The problem with the faster drop in grips strength for me/CFS versus healthy controls, is that something similar is seen in a number of illnesses...
I’m not quite sure what you want with your prevalence citation, but this Louis Nacul in study is interesting based on the British Columbia...
Good grief: clear reporting of a negative result, including that it contradicts earlier positive findings. That might seem like a backward step,...
Thanks. If my maths is right, 20% said they improved with CBT and physical function. So overall, it’s modestly unhelpful, compared with a GET,...
That’s interesting, but inevitably biased since people who did well on it are far less likely to find the survey. What were the comparison figures...
Looks like they do have some interesting data for Persistent Lyme disease, but the samples are too small annd the ME cases are meaningless given...
This isn't the main finding, but this MRI on a subset of effort preference participants while doing handgrip (I think) is very interesting and...
Bear in mind that an AUC = 0.5 is what you get from a coin toss.
It would be interesting to know what impact the menstrual cycle has on symptoms in other illnesses.
I fully agree with that, largely because of the excellent analysis you’ve done show that other medical charities fund a big proportion of the...
Separate names with a comma.