Only some illnesses are Mendelian diseases, meaning that one allele confers the disease phenotype. However, like you alluded to, the mechanism of...
Just as a brief note from skimming the paper, I’m always somewhat skeptical of proteasome findings on the basis of gene ontology since the pathway...
Thanks so much for your explanation of all this. I’m somewhat familiar with some of the research on metabolic sensing, but it’s quite out of my...
Thanks for the clarification!
Thanks for the updates!
Hello! I have a pretty good genomics (specifically transcriptomic) and machine learning background so I’d be able to comment on that, though I...
It’s quite baffling to me that brain retraining doesn’t actually encourage introspection into past experiences like traditional talk therapy. It...
I think that the term “epistemic injustice” can be misleading for anyone who isn’t familiar with it from philosophy—it has a specific definition...
Good point! If I remember correctly, it was a point that was brought up in Wilshire et al. as well. Coupled with the priming that the treatments...
While I'm genuinely sympathetic to discussions of epistemic injustice in ME/CFS, I think this paper should have clarified the difference between...
Same, I've decided not to engage anymore.
Update: I've gone back to taking a malic acid supplement in the evening, usually closer to bed time. Typically I'll do a small amount, maybe...
Good to know--I'd be interested to know how you feel tomorrow. It's wonderful that you found it easier to go up the hill! That was one of the...
Thanks for the update!! Just to compare, is this different from what you would normally expect after that level of activity? Does it normally...
Is it at all possible that the lung perfusion issues can cause differences in resting HR and RR? Or that they’re both just downstream of the same...
So then the question would be whether the brain is integrating all that information independently of metabolism, or whether it is simply tapped in...
Obviously it might not be feasible or available for everyone, but there are plenty of universities that offer “late-learning” programs...
Northwestern's still completely in the dark, we've (the grad students, at least) had no update since the news broke. We have a long COVID clinic...
Sorry, I think I added my edit right after you quoted me. I had just realized that they reported >0.9999 twice which makes this extremely unlikely...
For what it's worth (as non-simulated further validation of your earlier analysis), when I do differential gene expression analyses where I'm...
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