https://www.sciencedirect.com/science/article/pii/S2772892724000798 This review mentions that itaconate import has been observed in both T cells...
Thanks for letting me know! I think between me, you, and one other friend I’ve been chatting with privately, it seems consistent that malic acid...
Something I’ve been tossing around as a potential dissertation idea is to start with a broad group of individuals who have been diagnosed with or...
I don’t want to push it on anyone but since you already mentioned you’re looking:...
Absolutely! I wish I had access to a community of others pointing things out like this when I was first starting to learn immunology on my own...
That’s one of the things associated with aging. My former rotation lab also did some interesting work associating the length of a gene with...
No no you’re doing a great job—just wanted to point it out because this happens to be a field where the terminology can get so incredibly...
Thanks for putting together all these resources @hotblack! Just a quick note about the cytotoxic label: while generally it does refer to...
I haven’t had a chance to read the full paper but it’s interesting that the DHEA finding was replicated with my team’s LC paper, which also has...
For what it’s worth, some of my literature search turned up that the itaconate response can be triggered by interferon gamma as well. Meaning that...
I’ve been having the same line of thought—what is interesting to me is that succinate dehydrogenase (one of the TCA enzymes affected by itaconate...
That’s what we’re here for :) Explain like I’m brain-foggy: The baseline ability of the brain to carry out cognitive tasks is unchanged (CPU),...
I think the main difference is whether it feels like it gives you more energy/endurance within 15-30 minutes (more than the stimulant alone), or...
I just heard back from one of the folks that messaged me directly about sumac working for them—they confirmed that they also regularly take an...
Different labs work in different ways, some will run a very tight ship like what you describe. Either way, the one consistent feature for all grad...
That's very interesting--funnily enough, I noticed quite a change in the time frame of PEM once I started taking a stimulant for ME/CFS....
Most researchers, especially the ones doing work that doesn't need to be done in certain time constraints in a wet lab, are often working on...
I've actually chatted with a researcher who specializes in using electronic health record data for questions like this. There are lots of hospital...
Since they're hypothesizing that both increased exposure to COVID and extreme work stressors among healthcare workers are risk factors for LC, I...
A recent LC paper I co-authored also used the serum O-link assay. One of the models we tested was for predicting cognitive impairment as measured...
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