Explain like I'm brain-foggy: Malate is a TCA cycle metabolite critical for ATP production through oxidative phosphorylation. Its role in...
The reason I'm interested in this is a possible time course that could potentially line up with PEM, [edit: and the idea that short term...
Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation Gretchen L Seim, Emily C Britt,...
Additional background from the introduction:
Malate initiates a proton-sensing pathway essential for pH regulation of inflammation Yu-jia-nan Chen, Rong-chen Shi, Yuan-cai Xiang, Li Fan,...
Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity Feilong...
Hard to give an exact answer since my entire experience of ME changed quite dramatically with the stimulants. Pre-stimulants I was mostly...
Vyvanse and adderall, vyvanse gets converted into adderall (dextroamphetamine) in the body. Both are monoamine reuptake inhibitors acting on...
That's my biggest complaint with the NASEM definition. It basically boils down Long COVID to "anything that could ever happen to you other than...
Okay, having had a chance to revisit the paper: 1) It looks like the actual clustering (Fig 7A) was in fact done on flow cytometry markers and not...
"Our study found that staring at a wall was a cost-effective solution for type I diabetes, because staring at a wall is cheaper than insulin."
[IMG] Fig 3: Similarly no change in hemotological parameters between groups In the next section, examining biochemical parameters (Fig 4):...
[IMG] So it seems like they were investigating the hypothesis that post-COVID effects were due to viral damage to the genome because evidence of...
I think that they’re specifically looking for virus-induced DNA damage in cells, like what UV rays do that eventually leads to skin cancer....
I have a potential collaboration worked out where a generous research team might be able to carry out one preliminary experiment for me. Timeline...
I don’t have specific product suggestions but if you find something that works for you in every aspect except screen brightness, you can buy an...
The reagents necessary to use in the lab can get quite pricey depending on what you’re doing. Many grants do offer some level of discretionary...
Well then I hope my results get published someday because they might surprise you!
Not to further derail the thread, but it turns out I did read some of your group's work a few years ago when I was working on synovial...
That’s exactly my hunch, but it’s pure speculation at this point so I hope nobody puts too much faith on it until there’s data to back it up....
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