Some of those concerns are addressed in @Andy 's Q&A with Solve ME...
Q7. How much beer money would it take to visit Accumen Labs in Devon and jointly perform an experiment with John McLaren-Howard to resolve the...
Usually when there is such a big disagreement you need to get both parties in the same room and figure out why. I'm surprised the ME Association...
Q6. Paul Fisher presented detailed work into Mitochondrial function in ME/CFS plasma cells at the Australia conference hosted by Emerge. Has Karl...
Q5. The oxygen consumption plasma swap that Karl Morten reported on was fascinating, corroborating others findings that something in the plasma is...
Q3. In the NZ presentation 2 unidentified VIP metabolites were significantly elevated in a subset of patients. What work has been done to identify...
Q1. In the NZ presentation Karl Morten showed a 6 fold increase in Glutamate and a reduction in Glutamine. What needs to be done to validate this...
I'm beginning to think that GWAS isn't so great when there are multiple damaging mutations that are very common in the population in one...
Does anyone know if this is what Ian Lipkin presented at the NIH ME/CFS conference in April? If I remember right he was intending to do a similar...
It seems Norman Booth, had similar concerns about the state of the Neutrophils which he discussed with John Mclaren Howard the one who came up...
With $5MM per year in funding, one would think that would allow a full time person to be 100% dedicated to ME/CFS. Or is that $5MM being used to...
I agree with everything you say Tom about the importance of pilot studies. To be clear, a successful pilot study does not mean more NIH funding...
Unfortunately the paper written by the Klimas team using this approach is anything but robust. 23andMe is low quality and the data is full of...
@Chris Ponting Would it be possible for you to enquire whether the 100,000 Genomes project has ME/CFS data available? According to this article...
NIH-funded HRV Study announced for ME/CFS at Stony Brook University [MEDIA]
I thought this was interesting. This is similar to what Nancy Klimas is reporting in her videos about the differences between GWI and ME/CFS
Just to clarify the question. Naviaux second study after the first was published was 3 years ago. The second study has not yet been published...
Done. [MEDIA]
For the fun of it I took a look at the high p value phenotypes for IDO1 and IDO2. Not sure it means much for the metabolic trap theory, but it was...
If anyone is interested you can search by variant with the "Phewas" search option and you will get a table you can sort by p-value for that...
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