You are reminding me of Plato, @Eddie. There are other layers, at least some of which you may be very familiar with. I will need to reply in the...
Selective expression of cytokine receptors would do. There is every reason to think that will be a thing. But why the variation in how it goes...
That is the elephant in the room maybe. Neuroimmune communication has been talked about for decades. Cytokines making nerves feel lousy is easy...
And these are exactly the questions to entertain yourself with while doing the washing-up. Lymphocytes and slime mould cells will no doubt have...
Well, it took me nearly twenty years to write!
Sometimes its the unexpected things that are most worth thinking over carefully. Chris P has mentioned some further analysis of this study which I...
Not really. I am just being devil's advocate saying that maybe muscle itself is not part of the pathology in ME/CFSand that symptoms come from...
My understanding is that a big part of the problem may be that the people who specialise in diagnosing SFN do not understand it and one of the bad...
OK, the 'for me' there was a sleight of hand. It should really have been for that event, considered as here and now, even if to consider it we...
I think the trouble is that we have very little reliable information about this. I don't think symptoms of ME/CFS are consistent with neuropathy...
If this stuff interests you then I would strongly recommend reading Frege's Sinn und Bedeutung (but also some of the library of commentary in the...
Something like that.
The concern here would be that a drug that is supposed to wake you up will break blinding because being woken up will tell you that you are on the...
For any particular are of brain you are likely to have millions of neurons in a bank at a certain level of function that produce outputs in terms...
I was talking about separating no from not applicable in the abstract. For some propositions no and not specified may degenerate to the same...
I agree but I am confused because this was a cohort that has been trawled for SNPs as per usual GWAS rather than completely sequenced was it not?...
This takes a lot of unpacking and maybe more than we can do on a forum. Are you familiar with Frege (Sense and Reference) and, more importantly,...
I am not sure that anything 'explains' the correspondence between the physical dynamics and the sensed meaning. There just is a brute fact that...
The general doctrine is that a cell has only one output option - fire. It can fire at different rates but it is hard to see how that can provide...
Yes. For neurons at the level of experienced meaning we talk about I think it probably means N/A but the logic of this is very subtle and complex....
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