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Activity stream for all registered members at Science for ME.
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Peter Trewhitt liked MelbME's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
Mice vary a lot like people, especially in behavior. So if you are going to use behavioral measurements then you really need 10 or so...
Jun 2, 2024 at 10:37 PM -
alktipping liked MrMagoo's post in the thread [Thought experiment] In a random cohort of 100 ME/CFS patients (recent diagnosis via CCC), what can you know about them with 90%+ certainty?.
My friend was tired after a night out, she asked me if I ever feel so tired my bones hurt. I had no idea non-ME people could get that...
Jun 2, 2024 at 10:36 PM -
Peter Trewhitt liked MelbME's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
@butter. This is actually all you need as a summary. I didn't actually add much more. Just that an acute infection control would have...
Jun 2, 2024 at 10:36 PM -
Peter Trewhitt liked ME/CFS Skeptic's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
Can anyone explain why they pooled the IgG per subgroup? I would think that you get the most information if each participant's IgG was...
Jun 2, 2024 at 10:36 PM -
alktipping liked bobbler's post in the thread [Thought experiment] In a random cohort of 100 ME/CFS patients (recent diagnosis via CCC), what can you know about them with 90%+ certainty?.
Yes! before even I knew what was going on (so was desperately having to trudge through and keep doing), there was a point where someone...
Jun 2, 2024 at 10:36 PM -
Peter Trewhitt liked butter.'s post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
Could someone with more spoons summarise Dr. Edwards' and Dr. Armstrong's points in a few paragraphs? I will then use this this info...
Jun 2, 2024 at 10:36 PM -
Peter Trewhitt liked MelbME's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
The hot plate test shows a difference between Long COVID and acute COVID. Heat intolerance is a sign of dysautonomia. Perhaps anti-M3....
Jun 2, 2024 at 10:35 PM -
Peter Trewhitt liked SNT Gatchaman's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
Screengrabs from the SolveME presentation 3 weeks ago. At 16:10 below. [MEDIA]
Jun 2, 2024 at 10:35 PM -
Peter Trewhitt liked MelbME's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
That's cool, where is that from? Oh I just saw the embedded link. :thumbsdown:
Jun 2, 2024 at 10:35 PM -
Peter Trewhitt liked SNT Gatchaman's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
The Iwasaki/Putrino group look to have done that, per recent presentation of unpublished data. (Doesn't look like significant...
Jun 2, 2024 at 10:35 PM
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Peter Trewhitt liked Jonathan Edwards's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
If it was a good model I think drug companies would have sorted out the methodology and been using it for screening drugs for decades....
Jun 2, 2024 at 10:35 PM -
alktipping liked bobbler's post in the thread [Thought experiment] In a random cohort of 100 ME/CFS patients (recent diagnosis via CCC), what can you know about them with 90%+ certainty?.
Second this: "you always ended up with really bad tonisilitis (or something similar after tonsils were removed) every time you had a...
Jun 2, 2024 at 10:35 PM -
Peter Trewhitt liked MelbME's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
The controls aren't really there.. would have been nice to see what IgG from healthy with an infection does. Plus the pooling really...
Jun 2, 2024 at 10:35 PM -
Peter Trewhitt liked Jonathan Edwards's post in the thread Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+.
It is hard to wade through it all. Two things I noted: They pooled sera. That seems to me a disaster. If you pool 8 sera and give them...
Jun 2, 2024 at 10:35 PM -
alktipping liked bobbler's post in the thread [Thought experiment] In a random cohort of 100 ME/CFS patients (recent diagnosis via CCC), what can you know about them with 90%+ certainty?.
This is an important question to ask as it is exactly this we need to get others to understand. Particularly right now, as BPS are...
Jun 2, 2024 at 10:34 PM
