Review Post-acute Sequelae of SARS-CoV-2 Infection and Its Impact on Adolescents and Young Adults, 2024, Broussard et al.

Camille A. Broussard, MD, MPHa,*, Alba Azola, MDb,c, Peter C. Rowe, MDd
Pediatric Clinics of North America (2024)

• Post-acute sequelae of SARS CoV-2 infection (PASC) in adolescents and young adults (AYAs) presents heterogeneously, often with multisystem involvement.
  
  
• Between 3 and 6 months after infection, the most common persistent symptoms reported are fever, sore throat, fatigue or muscle weakness, and sleep disturbances.
  
  
• A subset of AYAs with persistent symptoms 6 months post-acute SARS CoV-2 infection meet criteria for myalgic encephalomyelitis/chronic fatigue syndrome, among whom fatigue, cognitive difficulties, post-exertional malaise, sleep disturbance, and symptoms of orthostatic intolerance are most common.
  
  
• PASC can be incredibly debilitating for AYAs in physical, social, and emotional domains which may interrupt normal adolescent development and transition to adulthood.
  
  
• Primary care providers have a key role in initial diagnosis, assessment, and treatment for the numerous AYAs affected by PASC.

https://www.pediatric.theclinics.com/article/S0031-3955(24)00043-9/abstract

 

What treatments?

 

They're recommending the usual POTS/MCAS/etc stuff - here's the treatments table: