@Jonathan Edwards @Invisible Woman @Maria1 @Jan @MsUnderstood @Bill @Daisybell We started discussing this on my Introduce Yourself thread, and it's time I tried to be sensible and get a bit sciencey, in my limited way. So, several of us have similar stories of migraines, thyroid problems, and hormone deficiencies, which we've addressed and rectified in hopes of improving our energy and general health. Alas, to no avail. I know that thyroid, adrenal and sex hormone production are 3 corners of a triangle, and all impact on migraine occurence. But idiotically, my neurologist, gynaecologist and endocrinologist have never looked at me as a complicated organism, with interlocking parts, but as "territory" that are their sole provenance, and other, "foreign parts" that are the domain of colleagues. It's infuriating. And the last 2 weeks, despite being slim and eating healthily, I'm suffering from what seems like hypoglycaemia. I'm very interested in what @Jonathan Edwards said about the underlying autoimmunity in Hashimoto's causing the ongoing symptoms despite treatment. But I have an interesting thing - a few years ago my results came back normal for anti - thryroglobulin antibodies. Do I still have Hashimoto's? I've no idea! So, people. Ideas? Theories? And, vitally, are we all treating our migraines optimally?