Indigophoton
Senior Member (Voting Rights)
Genetic editing has progressed rapidly over the past several years, in large part because of the development and refinement of CRISPR/Cas9 technologies. Put simply,CRISPR/Cas9 allows accurate targeting of and changes to genetic sequences within cells, and it is relatively quick and easy to implement. Its potential applications are vast, and recently a team led by JAX Professor Derya Unutmaz, M.D., evaluated its use in immune cells. In “Functional Interrogation of Primary Human T Cells via CRISPR Genetic Editing,” published in the Journal of Immunology, the researchers demonstrate the ability to target and disrupt specific genes and/or alter their expression levels, which has important implications for both immunology research and clinical treatments.
https://www.jax.org/news-and-insights/2018/july/human-immune-response#