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  1. SNT Gatchaman

    Review Type I interferons and endoplasmic reticulum stress in health and disease, 2020, Sprooten and Garg

    Type I interferons and endoplasmic reticulum stress in health and disease Sprooten; Garg Type I interferons (IFNs) comprise of pro-inflammatory cytokines created, as well as sensed, by all nucleated cells with the main objective of blocking pathogens-driven infections. Owing to this broad range...
  2. SNT Gatchaman

    Specific activation of the integrated stress response uncovers regulation of central carbon metabolism and lipid droplet biogenesis, 2024, Labbé et al

    Specific activation of the integrated stress response uncovers regulation of central carbon metabolism and lipid droplet biogenesis Labbé, Katherine; LeBon, Lauren; King, Bryan; Vu, Ngoc; Stoops, Emily H.; Ly, Nina; Lefebvre, Austin E. Y. T.; Seitzer, Phillip; Krishnan, Swathi; Heo, Jin-Mi...
  3. SNT Gatchaman

    Neuro-intestinal acetylcholine signalling regulates the mitochondrial stress response in Caenorhabditis elegans, 2024, Cornell+

    Neuro-intestinal acetylcholine signalling regulates the mitochondrial stress response in Caenorhabditis elegans Cornell, Rebecca; Cao, Wei; Harradine, Bernie; Godini, Rasoul; Handley, Ava; Pocock, Roger Neurons coordinate inter-tissue protein homeostasis to systemically manage cytotoxic stress...
  4. SNT Gatchaman

    The germline coordinates mitokine signaling, 2024, Shen et al.

    The germline coordinates mitokine signaling Koning Shen; Jenni Durieux; Cesar G. Mena; Brant M. Webster; C. Kimberly Tsui; Hanlin Zhang; Larry Joe; Kristen M. Berendzen; Andrew Dillin The ability of mitochondria to coordinate stress responses across tissues is critical for health. In C...
  5. SNT Gatchaman

    The extracellular matrix integrates mitochondrial homeostasis, 2024, Zhang et al.

    The extracellular matrix integrates mitochondrial homeostasis Hanlin Zhang; C. Kimberly Tsui; Gilberto Garcia; Larry K. Joe; Haolun Wu; Ayane Maruichi; Wudi Fan; Sentibel Pandovski; Peter H. Yoon; Brant M. Webster; Jenni Durieux; Phillip A. Frankino; Ryo Higuchi-Sanabria; Andrew Dillin SUMMARY...
  6. SNT Gatchaman

    Review Unraveling the Connection: Pain and Endoplasmic Reticulum Stress, 2024, Kawanaka et al.

    Unraveling the Connection: Pain and Endoplasmic Reticulum Stress Kawanaka, Ryoko; Jin, Hisayo; Aoe, Tomohiko Pain is a complex and multifaceted experience. Recent research has increasingly focused on the role of endoplasmic reticulum (ER) stress in the induction and modulation of pain. The ER...
  7. SNT Gatchaman

    Review SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19, 2024, Guarnieri et al.

    SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19 Guarnieri; Haltom; Albrecht; Lie; Olali; Widjaja; Ranshing; Angelin; Murdock; Wallace To determine the effects of SARS-CoV-2 infection on cellular metabolism, we conducted an exhaustive survey of the cellular metabolic...
    • SNT Gatchaman
    • Thread
    • atf6 cgas-sting epigenetics fgf21 gdf15 glycolysis hif-1 histone innate immune system integrated stress response interferon metabolic reprogramming metabolism mitochondria oxidative phosphorylation pentose phospate pathway perk tlr-9 upr
    • Replies: 2
    • Forum: Long Covid research
  8. SNT Gatchaman

    Review Mitochondrial quality control pathways sense mitochondrial protein import, 2023, Laurie P. Lee-Glover and Timothy E. Shutt

    Mitochondrial quality control pathways sense mitochondrial protein import Laurie P. Lee-Glover; Timothy E. Shutt Mitochondrial quality control (MQC) mechanisms are required to maintain a functional proteome, which enables mitochondria to perform a myriad of important cellular functions from...
    • SNT Gatchaman
    • Thread
    • autophagy cell signalling fgf21 integrated stress response metabolism mitochondria mitophagy steroids unfolded protein response upr
    • Replies: 1
    • Forum: Other health news and research
  9. SNT Gatchaman

    Review Sphingolipids and their metabolism in physiology and disease, 2017, Hannun, Yusuf A. and Obeid, Lina M.

    Sphingolipids and their metabolism in physiology and disease Hannun, Yusuf A.; Obeid, Lina M. Studies of bioactive lipids in general and sphingolipids in particular have intensified over the past several years, revealing an unprecedented and unanticipated complexity of the lipidome and its many...
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    • Thread
    • ceramide endoplasmic reticulum er stress golgi histone lipid droplets lipid metabolism lipid rafts lipids s1pr sphingolipids sphingomyelin upr
    • Replies: 5
    • Forum: Other health news and research
  10. SNT Gatchaman

    Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture, 2023, Davies et al.

    Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture Jonathan P. Davies; Athira Sivadas; Katherine R. Keller; Brynn K. Roman; Richard J.H. Wojcikiewicz; Lars Plate Coronaviruses (CoV), including SARS-CoV-2, modulate host proteostasis...
  11. SNT Gatchaman

    Review Intracellular to Interorgan Mitochondrial Communication in Striated Muscle in Health and Disease, 2023, Boardman, Wüst et al.

    Intracellular to Interorgan Mitochondrial Communication in Striated Muscle in Health and Disease Boardman, Neoma T; Trani, Giulia; Scalabrin, Marco; Romanello, Vanina; Wüst, Rob C I Mitochondria sense both biochemical and energetic input in addition to communicating signals regarding the...
  12. SNT Gatchaman

    Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle, 2022, McNally et al.

    Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle McNally, Ben D.; Ashley, Dean F.; Hänschke, Lea; Daou, Hélène N.; Watt, Nicole T.; Murfitt, Steven A.; MacCannell, Amanda D. V.; Whitehead, Anna; Bowen, T. Scott; Sanders...
  13. SNT Gatchaman

    Preprint Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis, 2023, Li et al.

    Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis Jeson J Li; Nan Xin; Chunxia Yang; Larrisa A Tavizon; Ruth Hong; Travis I Moore; Rebecca G Tharyan; Adam Antebi; Hyun-Eui Kim Maintaining protein homeostasis is essential...
  14. SNT Gatchaman

    Hypoxia activates the unfolded protein response signaling network: An adaptive mechanism for endometriosis, 2022, Zhou et al.

    Hypoxia activates the unfolded protein response signaling network: An adaptive mechanism for endometriosis Zhou, Yong; Jin, Yang; Wang, Yuan; Wu, Ruijin Endometriosis (EMS) is a chronic gynecological disease that affects women of childbearing age. However, the exact cause remains unclear. The...
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