Insights into Pathophysiological Pathways in ME/CFS Through Genetic Correlation and Mendelian Randomization
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-acute infection syndromes (PAIS) are multisystem disorders involving immune, vascular, neuroinflammatory...
Genomic interplay between deployment exposures and Gulf War illness in Million Veteran Program participants
Abstract
Veterans of the 1990–1991 Gulf War (GW) experienced an elevated burden of chronic health conditions, most notably Gulf War Illness (GWI). While the disease etiology remains...
SGLT2 inhibitors prevent long-COVID-associated cognitive and pain symptoms in type 2 diabetes patients
Background
Long COVID presents significant health challenges, especially for patients with type 2 diabetes. Emerging evidence suggests that sodium-glucose cotransporter-2 (SGLT2) inhibitors...
The Coronavirus Disease 2019 Pandemic is Associated with a Substantial Rise in Frequency and Severity of Presentation of Youth-Onset Type 2 Diabetes
Published: 2022
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Objectives:
To evaluate the frequency and severity of new cases of youth-onset...
HbA1c and leukocyte mtDNA levels as major factors associated with post-COVID-19 syndrome in type 2 diabetes patients
Anton Matviichuk, Viktoriia Yerokhovych, Yeva Ilkiv, Dmytro Krasnienkov, Veronika Korcheva, Oleksandr Gurbych, Anna Shcherbakova, Pavlina Botsun, Tetyana Falalyeyeva, Oksana...
Highlights
Longitudinal multiomics associate PASC with autoantibodies, viremia and comorbidities
Reactivation of latent viruses during initial infection may contribute to PASC
Subclinical autoantibodies negatively correlate with anti-SARS-CoV-2 antibodies
Gastrointestinal PASC uniquely present...
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