The Critical Role of the Bile Acid Receptor TGR5 in Energy Homeostasis: Insights into Physiology and Therapeutic Potential
Zangerolamo, Lucas; Carvalho, Marina; Barbosa, Helena C. L.
Over the past decades, bile acids have been recognized as important signaling molecules with significant roles...
TUDCA is a hydrophilic bile acid that is produced in the liver. It is used for the treatment of chronic cholestatic liver diseases and for gallstone. TUDCA is orally bioavailable and blood–brain barrier permeable. Bile salts, including TUDCA, play a role in intestinal homeostasis by controlling...
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