Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome
Lisse Decraecker; María Cuende Estévez; Samuel Van Remoortel; Runze Quan; Nathalie Stakenborg; Zheng Wang; Elisabetta De Marco; Alexandre Denadai-Souza; Maria Francesca Viola; Sonia Garcia Caraballo; Stuart Brierley; Yasuhiro...
STING recognition of viral dsDNA by nociceptors mediates pain in mice
https://www.sciencedirect.com/science/article/pii/S0889159124004823
Highlights
Nociceptors can directly sense viral nucleic acids, such as dsDNA derived from herpes and vaccinia viruses.
Cytosolic dsDNA causes nocifensive...
Broadening the Genetic Spectrum of Painful Small-Fiber Neuropathy through Whole-Exome Study in Early-Onset Cases
Misra, Kaalindi; Ślęczkowska, Milena; Santoro, Silvia; Gerrits, Monique M.; Mascia, Elisabetta; Marchi, Margherita; Salvi, Erika; Smeets, Hubert J. M.; Hoeijmakers, Janneke G. J...
Exercise exerts a wide range of beneficial effects for healthy physiology1. However, the mechanisms regulating an individual’s motivation to engage in physical activity remain incompletely understood.
An important factor stimulating the engagement in both competitive and recreational exercise...
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