Analysis of Transient Receptor Potential Ion Channels in ME/CFS
Eaton-Fitch, Natalie; Muraki, Katsuhiko; Sasso, Etianne Martini; Magawa, Chandi; Marshall-Gradisnik, Sonya
This chapter provides a comprehensive overview of methodologies currently employed to study ion channels, particularly...
Low-Dose Naltrexone restored TRPM3 ion channel function in Natural Killer cells from long COVID patients
Etianne Martini Sasso, Natalie Eaton-Fitch, Peter Kenneth Smith, Muraki Katsuhiko, Sonya Marshall-Gradisnik
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Abstract
Long COVID is a multisystemic condition that includes...
Edit: This thread includes several other threads merged with it.
Some earlier threads on this team's work:
The Courier Mail: Australian scientists prove CFS is real and have discovered a test for it
Dec 2017 to Jan 2018
Don Staines and Griffith
Aug 2018
Australia - Parliamentarians learn...
australia
channelopathy
charity
collaborative research
conference
funding
griffith university
marshall-gradisnik
me australia
me/cfs
meet the scientists
melastatin
ncned
staines
trpm3
Full title:
Potential pathophysiological role of the ion channel TRPM3 in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and the therapeutic effect of low-dose naltrexone
Abstract
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating disease with a broad...
https://www.frontiersin.org/journals/cell-and-developmental-biology/articles/10.3389/fcell.2021.635659/full
open access
Already for centuries, humankind is driven to understand the physiological and pathological mechanisms that occur in our brains. Today, we know that ion channels play an...
Abstract
Gulf War Illness (GWI) is a chronic condition characterized by multisystem symptoms that still affect up to one-third of veterans who engaged in combat in the Gulf War three decades ago. The aetiology of GWI is mainly explained by exposure to multiple toxic agents, vaccines, and...
Anti-Nociceptive Effects of Sphingomyelinase and Methyl-Beta-Cyclodextrin in the Icilin-Induced Mouse Pain Model
Horváth, Ádám; Steib, Anita; Nehr-Majoros, Andrea; Kántás, Boglárka; Király, Ágnes; Racskó, Márk; Tóth, Balázs István; Szánti-Pintér, Eszter; Kudová, Eva; Skoda-Földes, Rita; Helyes...
Full title: Investigation into the restoration of TRPM3 ion channel activity in post COVID-19 condition: a potential pharmacotherapeutic target
Recently, we reported that post COVID-19 condition patients also have Transient Receptor Potential Melastatin 3 (TRPM3) ion channel dysfunction, a...
Abstract
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious disorder of unknown aetiology. While the pathomechanism of ME/CFS remains elusive, reduced natural killer (NK) cell cytotoxic function is a consistent immunological feature. NK cell effector functions...
The effect of IL-2 stimulation and treatment of TRPM3 on channel co-localisation with PIP2 and NK cell function in myalgic encephalomyelitis/chronic fatigue syndrome patients
Natalie Eaton-Fitch,
Hélène Cabanas,
Stanley du Preez,
Donald Staines &
Sonya Marshall-Gradisnik
Abstract...
Full title: Potential therapeutic benefit of Low Dose Naltrexone in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Role of Transient Receptor Potential Melastatin 3 ion channels in pathophysiology and treatment
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating...
"Naltrexone restores impaired transient receptor potential melastatin 3 ion channel function in natural killer cells from myalgic encephalomyelitis/chronic fatigue syndrome patients"
https://www.frontiersin.org/articles/10.3389/fimmu.2019.02545/abstract
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