trial design

  1. MSEsperanza

    Basic questions on terms and methodology used in clinical trials

    As the title indicates -- a thread for lay people like me who have no or only superficial knowledge of trial methodology and statistics to ask some basic questions and hopefully get answers from more knowledgeable forum members.
  2. C

    Completeness of clinical evidence citation in trial protocols: A cross-sectional analysis, Sheng et al

    Completeness of clinical evidence citation in trial protocols: A cross-sectional analysis, Cell Med, Sheng, Feldhake, Zarin, Kimmelman, 2022. Summary Background Human protection policies require assessment of how proposed clinical trials relate to prior and ongoing studies testing similar...
  3. MSEsperanza

    What's the difference between using symptoms for making a diagnosis in clinical care vs measuring a treatment effect in clinical trials? (Discussion)

    As the title indicates. Proponents of therapist delivered treatments like psychotherapy or exercise repeatedly rejected the argument that relying solely on subjective outcomes in open label trials to assess the effectiveness of said treatments was a bad idea. In their criticism on the NICE...
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