systemic lupus erythematosus

Increased proportion of CD56bright natural killer cells in active and inactive systemic lupus erythematosus Abstract Summary Natural killer (NK) cells belong to the innate immune system but can also affect adaptive immune reactions. This immune regulatory function is often ascribed to the...

The Role of SARS-CoV-2 Nucleocapsid Protein Persistence in Inducing Chronic Type I Interferon and Mitochondrial Dysfunction. Andreas Koenig; Mohammad Quasem; Benjamin Zink; Doniyorbek Abdulla-Zoda; Priyanka Karunanidhi; Karolina Sienko; Christian Geier; Venkatesh Jayaraman; Rabia Malik; Kanza...

Abstract Aberrant immune responses to viral pathogens contribute to pathogenesis, but our understanding of pathological immune responses caused by viruses within the human virome, especially at a population scale, remains limited. We analyzed whole-genome sequencing datasets of 6,321 Japanese...

Exploring the shared mechanism of fatigue between systemic lupus erythematosus and myalgic encephalomyelitis/chronic fatigue syndrome: monocytic dysregulation and drug repurposing Daisi Zheng, Xiaolong Li, Qingmiao Zhu, Zhiyan Huang, Peicheng Wang, Ting Zhao [Provisionally accepted] Edit: Now...

Interferon subverts an AHR–JUN axis to promote CXCL13+ T cells in lupus Law, Calvin; Wacleche, Vanessa Sue; Cao, Ye; Pillai, Arundhati; Sowerby, John; Hancock, Brandon; Horisberger, Alice; Bracero, Sabrina; Skidanova, Viktoriya; Li, Zhihan; Adejoorin, Ifeoluwakiisi; Dillon, Eilish; Benque, Isaac...

Risk of autoimmune diseases in patients with COVID-19: A retrospective cohort study Renin Chang, Thomas Yen-Ting Chen, Shiow-Ing Wang, Yao-Min Hung, Hui-Yuan Chen, Cheng-Chung James Weic Background There are a growing number of case reports of various autoimmune diseases occurring after...

Dall'Era, M., Bruce, I. N., Gordon, C., Manzi, S., McCaffrey, J., & Lipsky, P. E. (2019). Current challenges in the development of new treatments for lupus. Annals of the rheumatic diseases, 78(6), 729–735. https://doi.org/10.1136/annrheumdis-2018-214530...

Le Sueur, H., Bruce, I. N., Geifman, N., & MASTERPLANS Consortium (2020). The challenges in data integration - heterogeneity and complexity in clinical trials and patient registries of Systemic Lupus Erythematosus. BMC medical research methodology, 20(1), 164...

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