sodium channels

I am still reading this… this is a very good summary by some leading researchers about the difficulties they have encountered in trying to develop non-opioid painkillers using the sodium channel Nav1.8. It’s been a difficult and perplexing process and there’s an immense amount of pressure to...

Microneurography Reveals Unmyelinated Small Nerve Fiber Dysfunction in Long COVID OBJECTIVE To review the microneurography findings of long coronavirus disease 2019 (COVID) patients who presented to the clinic with multisystem involvement affecting neurological, cardiovascular...

SARS-CoV-2 N protein interacts with Nav1.7 to promote pathological pain Liu, Jin-Kun; Zhou, Zi-Su; Wang, Shu-Hang; Zuo, Shi-Yu; Lu, Xiao-Fan; He, Ying; Tang, Hao; Xie, Yan; Xie, Man-Xiu; Zhang, Xiao-Long Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome...

Identification and targeting of a unique NaV1.7 domain driving chronic pain Gomez, Kimberly; Stratton, Harrison J.; Duran, Paz; Loya, Santiago; Tang, Cheng; Calderon-Rivera, Aida; François-Moutal, Liberty; Khanna, May; Madura, Cynthia L.; Luo, Shizhen; McKiver, Bryan; Choi, Edward; Ran, Dongzhi...

Killian L’Herondelle,1 Matthieu Talagas,1,2 Olivier Mignen,3Laurent Misery,1,2 and Raphaele Le Garrec1,* (French researchers) Abstract Ciguatera fish poisoning (CFP), the most prevalent seafood poisoning worldwide, is caused by the consumption of tropical and subtropical fish contaminated with...