seahorse

  1. W

    Webinar: Understanding ME: Investigating cellular and body-wide features of ME, Dr Daniel Missailidis, PhD

    ME Group Australia YouTube Channel posted a talk with @DMissa "Understanding ME: Investigating cellular and body-wide features of ME" Dr Daniel Missailidis, PhD, discusses his work over the last 10 years in a very easy to understand way. The biggest finding to date from this team has been...
  2. Dolphin

    Heat vs. Fatigue: Hyperthermia as a Possible Treatment Option for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS), 2025, Hochecker

    https://www.mdpi.com/1422-0067/26/11/5339# Open Access Article Heat vs. Fatigue: Hyperthermia as a Possible Treatment Option for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) by Barbara Hochecker 1,*, Katja Matt 1, Melanie Scherer 1, Alica Meßmer 1, Alexander von Ardenne 2...
    • Dolphin
    • Thread
    • autophagy bip grp78 hsp hyperthermia mitochondria oxygen use seahorse sod2 ulk
    • Replies: 18
    • Forum: ME/CFS research
  3. SNT Gatchaman

    Real-Time Measurement of Mitochondrial Function and Glycolysis in Lymphoblastoid Cell Lines, 2025, Katsaros,Missailidis, Annesley

    Real-Time Measurement of Mitochondrial Function and Glycolysis in Lymphoblastoid Cell Lines Katsaros, Tina; Missailidis, Daniel; Annesley, Sarah J. Cells require energy in the form of ATP to function. The two main ways in which cells generate energy in mammalian cells is through glycolysis and...
  4. SNT Gatchaman

    Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications, 2025, Semo+

    Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications Semo, Dilvin; Shomanova, Zornitsa; Sindermann, Jürgen; Mohr, Michael; Evers, Georg; Motloch, Lukas J.; Reinecke, Holger; Godfrey, Rinesh; Pistulli, Rudin Cardiovascular...
    • SNT Gatchaman
    • Thread
    • caspase caspase-1 glutathione grp78 il-1b immunoparalysis inflammasome mitochochria monocytes mtdna oxidative stress reactive oxygen species seahorse tlr-4 tlr-9
    • Replies: 2
    • Forum: Long Covid research
  5. SNT Gatchaman

    Specific activation of the integrated stress response uncovers regulation of central carbon metabolism and lipid droplet biogenesis, 2024, Labbé et al

    Specific activation of the integrated stress response uncovers regulation of central carbon metabolism and lipid droplet biogenesis Labbé, Katherine; LeBon, Lauren; King, Bryan; Vu, Ngoc; Stoops, Emily H.; Ly, Nina; Lefebvre, Austin E. Y. T.; Seitzer, Phillip; Krishnan, Swathi; Heo, Jin-Mi...
  6. Mij

    Soluble IL-2R impairs muscle cell mitochondrial respiration in fatigued individuals with post-acute sequelae of COVID-19, 2024, Peterson Brown

    Abstract Post-acute sequelae of COVID (PASC) persist in many patients for weeks and months after recovery from initial SARS-CoV-2 infection. Recent evidence suggests that pathological changes in skeletal muscle may contribute significantly to ongoing pain and fatigue, particularly...
    • Mij
    • Thread
    • cd25 il-2 il-2r jak-stat mitochondrial dysfunction muscle biopsy oxygen use seahorse t-cells
    • Replies: 10
    • Forum: Long Covid research
  7. Dolphin

    Mitochondrial function in patients affected with fibromyalgia syndrome is impaired and correlates with disease severity, 2024, Macchi

    https://www.researchsquare.com/article/rs-4654793/v1 Mitochondrial function in patients affected with fibromyalgia syndrome is impaired and correlates with disease severity Chiara Macchi1 Andrea Giachi1 Isabella Fichtner1 Silvia Pedretti1 Piercarlo Sarzi Puttini2 Nico Mitro1 Alberto...
  8. SNT Gatchaman

    Preprint Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST, 2024, Sprenger et al.

    Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST Hans-Georg Sprenger; Melanie J. Mittenbühler; Yizhi Sun; Jonathan G. Van Vranken; Sebastian Schindler; Abhilash Jayaraj; Sumeet A. Khetarpal; Ariana Vargas-Castillo; Anna M. Puszynska; Jessica...
  9. Dolphin

    Trial Report Heat treatment in health and disease: How water-filtered infrared-A (wIRA irradiation affects key cellular mechanisms in ME/CFS, 2024, Hochecker

    https://www.sciencedirect.com/science/article/abs/pii/S0306456524000317 Journal of Thermal Biology Available online 21 February 2024, 103813 In Press, Journal Pre-proof Heat treatment in health and disease: How water-filtered infrared-A (wIRA irradiation affects key cellular mechanisms in...
    • Dolphin
    • Thread
    • ampk atg7 autophagy hsp70 infrared mitochondria seahorse sirt
    • Replies: 5
    • Forum: ME/CFS research
  10. SNT Gatchaman

    Altered mitochondrial respiration in peripheral blood mononuclear cells of post-acute sequelae of SARS-CoV-2 infection, 2024, Dirajlal-Fargo et al.

    Altered mitochondrial respiration in peripheral blood mononuclear cells of post-acute sequelae of SARS-CoV-2 infection Dirajlal-Fargo; Maison; Durieux; Andrukhiv; Funderburg; Ailstock; Gerschenson; Mccomsey Peripheral blood mononuclear cells (PBMC) mitochondrial respiration was measured ex vivo...
  11. Andy

    Time dependent changes in the bioenergetics of PBMCs: processing time, collection tubes and cryopreservation effects 2023 Werner et al

    Full title: Time dependent changes in the bioenergetics of peripheral blood mononuclear cells: processing time, collection tubes and cryopreservation effects Objectives: Bioenergetic measurements in peripheral blood mononuclear cells (PBMCs) using high-throughput respirometry is a promising...
  12. E

    Prolonged indoleamine 2,3-dioxygenase-2 activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection, 2023, Guo et al

    Prolonged indoleamine 2,3-dioxygenase-2 activity and associated cellular stress in post-acute sequelae of SARS-CoV-2 infection Background Post-acute sequela of SARS-CoV-2 infection (PASC) encompass fatigue, post-exertional malaise and cognitive problems. The abundant expression of the...
    • EndME
    • Thread
    • 2023 aryl hydrocarbon receptor citric acid cycle ido2 kynurenine long covid newspapers seahorse
    • Replies: 14
    • Forum: Long Covid research
  13. SNT Gatchaman

    SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution, 2020, Argüello et al.

    SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution Rafael J. Argüello; Alexis J. Combes; Remy Char; Julien-Paul Gigan; Ania I. Baaziz; Evens Bousiquot; Voahirana Camosseto; Bushra Samad; Jessica Tsui; Peter Yan; Sebastien Boissonneau...
  14. SNT Gatchaman

    Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire, 2023, Gordon-Lipkin et al.

    Primary oxidative phosphorylation defects lead to perturbations in the human B cell repertoire Gordon-Lipkin, Eliza M.; Banerjee, Payal; Franco, Jose Luis Marin; Tarasenko, Tatiana; Kruk, Shannon; Thompson, Elizabeth; Gildea, Derek E.; Zhang, Suiyuan; Wolfsberg, Tyra G.; NISC Comparative...
  15. B

    Altered Fatty Acid Oxidation in Lymphocyte Populations of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2023, Maya et al

    https://www.mdpi.com/1422-0067/24/3/2010 Abstract Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a disabling multisystem illness in which individuals are plagued with fatigue, inflammatory symptoms, cognitive dysfunction, and the hallmark symptom, post-exertional malaise. While...
    • Braganca
    • Thread
    • fatty acid metabolism maureen hanson metabolism natural killer cells nk cells seahorse t cells t-cells
    • Replies: 15
    • Forum: ME/CFS research
  16. Hoopoe

    WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et al

    The pre-publication thread has been merged with the thread on the paper. Link to paper's abstract here...
    • Hoopoe
    • Thread
    • bip endoplasmic reticulum er stress exercise intolerance grp78 mitochondrial function mouse model muscle biopsy p53 perk salubrinal seahorse study idea wasf3 wave3
    • Replies: 251
    • Forum: ME/CFS research
  17. Dolphin

    Impaired Mitochondrial Bioenergetics Function in Pediatric Chronic Overlapping Pain Conditions w/ Functional Gastrointestinal Disorders,2021,Chelimsky

    Not sure which forum to post this to but it looks interesting. https://www.hindawi.com/journals/prm/2021/6627864/ Research Article | Open Access Volume 2021 |Article ID 6627864 | https://doi.org/10.1155/2021/6627864 Impaired Mitochondrial Bioenergetics Function in Pediatric Chronic...
    • Dolphin
    • Thread
    • 2021 functional gastrointestinal disorder mitochondria paediatric paper seahorse spare respiratory capacity young people
    • Replies: 0
    • Forum: ME/CFS research
  18. Kalliope

    biomolecules: Bioenergetic and Proteomic Profiling of Immune Cells in ME/CFS Patients: An Exploratory Study - Fernandez-Guerra et al - 2021

    biomolecules: Bioenergetic and Proteomic Profiling of Immune Cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients: An Exploratory Study Fernandes-Guerra et al Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a heterogeneous, debilitating, and complex...
    • Kalliope
    • Thread
    • 2021 acetyl co a atp coenzyme a denmark fernandez-guerra me/cfs metabolomics mitochondria mitochondrial dysfunction paper proteomics pyruvate dehydrogenase complex seahorse
    • Replies: 9
    • Forum: ME/CFS research
  19. Sly Saint

    Measuring mitochondrial function

    Copied post this might be of interest from 2007 Assay: Measurement of Mitochondrial Function https://www.genengnews.com/magazine/80/assay-measurement-of-mitochondrial-function/
  20. John Mac

    An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients Missailidis et al. 2019

    https://www.preprints.org/manuscript/201909.0043/v1
    • John Mac
    • Thread
    • atp complex v fisher lymphoblasts me/cfs missailidis mitochondria mtor seahorse
    • Replies: 69
    • Forum: ME/CFS research
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