risk factors

Risk Factors for Long COVID Among Individuals with Noninfectious Uveitis in a Large United States Claims Database PURPOSE Patients with noninfectious uveitis (NIU) may be more susceptible to complications of COVID-19, including long COVID, yet limited research has evaluated this outcome in NIU...

IL-6 Receptor Antagonists and Severe Post-COVID-19 Outcomes: An Emulated Target Trial BACKGROUND Interleukin-6 (IL-6) is a cytokine that plays a key role in systemic hyperinflammation and may mediate the relationship between acute COVID-19 and severe long-term outcomes such as Long COVID or...

The age paradox in post-infectious sequelae: physiological reserve outweighs chronological age in Long COVID susceptibility BACKGROUND Older age is widely considered a risk factor for post-acute sequelae of SARS-CoV-2 infection (PASC), typically attributed to immunosenescence and inflammaging...

Long COVID following SARS-CoV-2 infection during pregnancy: An observational study in a large Italian hospital during the COVID-19 pandemic INTRODUCTION Despite mounting evidence on Long COVID, data regarding its impact on women infected during pregnancy remains scarce. This study aimed to...

Coffee and Tea Intake, Dementia Risk, and Cognitive Function IMPORTANCE Evidence linking coffee and tea to cognitive health remains inconclusive, and most studies fail to differentiate caffeinated from decaffeinated coffee. OBJECTIVE To investigate associations of coffee and tea intake with...

SARS-CoV-2 reinfections and subsequent risk of hospital-diagnosed post-acute sequelae in Denmark 2020–2022: a nationwide cohort study BACKGROUND Post-acute sequelae of COVID-19 (PASC), or long COVID, are a public health concern. While most recover from SARS-CoV-2 infections within weeks, some...

Impact of COVID‑19 infection on subsequent prescriptions of autonomic dysfunction pharmacotherapy: a nationwide propensity‑score‑matched Cohort study in Japan Daisuke Miyamori; Masanori Ito BACKGROUND Autonomic dysfunction, including orthostatic hypotension and postural tachycardia syndrome...

Deaths potentially averted by small changes in physical activity and sedentary time: an individual participant data meta-analysis of prospective cohort studies BACKGROUND The effects of small, realistic changes in physical activity and sedentary behaviour on population-level mortality are...

Neurological sequela of COVID-19 in adults with multiple sclerosis BACKGROUND Possible interactions in neuropsychiatric presentations of multiple sclerosis (MS) and COVID-19 may occur, which has been proposed in previous, albeit limited, literature. OBJECTIVES Examine COVID-19 disease...

Factors associated with long COVID among cancer survivors: A population-based analysis Case; Sabik; Grant INTRODUCTION Cancer survivors endure unique immune system suppression as a result of their cancer treatment, potentially making them susceptible to long COVID in ways that differ from the...

Understanding how social determinants of health shape Long COVID outcomes: a rapid review of evidence [Line breaks added] Background Long COVID affects over 65 million people worldwide, yet the impact of social determinants of health (SDoH), such as socioeconomic status, race/ethnicity...

Impact of Prior History of Traumatic Stress on Autonomic and Multi-System Symptoms Following COVID-19 Infection [Line breaks added] Background Persistent symptoms of autonomic dysregulation are common after COVID-19 infection and may result from alterations in central and/or peripheral...

SARS-CoV-2 Infection Is Associated With an Increased Risk of Hospital-Treated Infectious Mononucleosis due to EBV: National Register-Based Cohort Study There is evidence that persistent dysregulation of the immune system caused by SARS-CoV-2 infection may increase susceptibility to other...

Increase in Fall-Related Fatalities in the Home Following the COVID-19 Pandemic Onset BACKGROUND Falls are a leading cause of injury and death in older adults (age ≥ 65 years). The onset of the COVID-19 pandemic in the United States (US) marked a transition into a period of greater social...

Long COVID and Reduced Thrombosis in Antihistamine Treated Patients: An Observational Study in the Metropolitan Area of Barcelona BACKGROUND Early evidence from a nursing home in Yepes (Toledo, Spain) indicated that antihistamines combined with azithromycin prevented deaths and...

MTHFR allele and one-carbon metabolic profile predict severity of COVID-19 While the public health burden of SARS-CoV-2 infection has lessened due to natural and vaccine-acquired immunity, emergence of less virulent variants, and antiviral medications, COVID-19 continues to take a significant...

Occupational determinants of Long COVID in the population-based COVICAT cohort OBJECTIVES Occupational factors affect SARS-CoV-2 infection risk, but the occupational factors associated with Long COVID (LC) are unknown. We aimed to address this issue using individual data in a population-based...

Functional Neurological Disorder Following COVID-19: Results From a Large International Electronic Health Record Database BACKGROUND Following COVID-19, an increased risk of neurological and psychiatric sequelae has been reported. Viral illnesses commonly trigger functional neurological...

Whole genome sequence meta-analyses reveal common and rare genetic associations with critical COVID-19 In susceptible patients, COVID-19 causes life-threatening disease driven by immune-mediated inflammatory lung injury. We have previously shown that multiple common host genetic variants are...

Vitamin D intake and multiple sclerosis risk in the Norwegian Mother, Father and Child cohort BACKGROUND Higher vitamin D has consistently been associated with a lower multiple sclerosis (MS) risk, but some controversy remains about whether this is due to vitamin D itself or sunlight. METHODS...