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randomisation
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(…) overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors, Wang, Guyatt+, 2023
Compelling evidence from meta-epidemiological studies demonstrates overestimation of effects in randomized trials that fail to optimize randomization and blind patients and outcome assessors [A number of authors are from Gordon Guyatt’s group at McMaster University in Canada] Objective To...- cassava7
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- bias blinding outcome measures overestimation randomisation rct research methodology risk of bias
- Replies: 7
- Forum: Research methodology news and research
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Real-world studies no substitute for RCTs in establishing efficacy (2019)- Gerstein McMurray Holman
Real-world studies no substitute for RCTs in establishing efficacy January 19, 2019 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(18)32840-X/fulltext?utm_campaign=lancet&utm_content=83224321&utm_medium=social&utm_source=twitter&hss_channel=tw-27013292#.XEgvxfcH2L0.twitter...- Sly Saint
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- bias randomisation rct research methodology
- Replies: 9
- Forum: Research methodology news and research