Systemic Multi-Omics Analysis Reveals Interferon Response Heterogeneity and Links Lipid Metabolism to Immune Alterations in Severe COVID-19
Ronaldo Lira-Junior; Anoop Ambikan; Axel Cederholm; Ssefanit Rezene; Flora Mikaeloff; Sara Svensson Akusjarvi; Ahmet Yalcinkaya; Xi Chen; Maike Sperk...
A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants
Farley, Scotland E.; Kyle, Jennifer E.; Leier, Hans C.; Bramer, Lisa M.; Weinstein, Jules B.; Bates, Timothy A.; Lee, Joon-Yong; Metz, Thomas O.; Schultz, Carsten; Tafesse, Fikadu G.
A comprehensive...
Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Results from HCHS/SOL
Moon, Jee-Young;Chai, Jin Choul;Yu, Bing;Song, Rebecca J.;Chen, Guo-Chong;Graff, Mariaelisa;Daviglus, Martha L.;Chan, Queenie;Thyagarajan, Bharat;Castaneda, Sheila F.;Grove...
Full title: Chronic inflammation, neuroglia dysfunction, and plasmalogen deficiency as a new pathobiological hypothesis addressing the overlap between post-COVID-19 symptoms and myalgic encephalomyelitis/chronic fatigue syndrome
Highlights
Plasmalogens (Pls) are lipids containing a...
Abstract
Background
Peroxisomes are single membrane-bound organelles named for their role in hydrogen peroxide production and catabolism. However, their cellular functions extend well beyond reactive oxygen species (ROS) metabolism and include fatty acid oxidation of unique substrates that...
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