pca

  1. Yann04

    Adjusting for principal components can induce collider bias in genome-wide association studies, 2024, Grinde et al

    Abstract: Principal component analysis (PCA) is widely used to control for population structure in genome-wide association studies (GWAS). Top principal components (PCs) typically reflect population structure, but challenges arise in deciding how many PCs are needed and ensuring that PCs do not...
  2. Samuel

    Circadian regulation of allergic reactions by the mast cell clock in mice, 2013, Nakamura et al

    https://pubmed.ncbi.nlm.nih.gov/24060274/ Abstract Background: It remains elusive how allergic symptoms exhibit prominent 24-hour variations. In mammals the circadian clocks present in nearly all cells, including mast cells, drive the daily rhythms of physiology. Recently, we have shown that...
    • Samuel
    • Thread
    • allergy bmcmc bone marrow–derived cultured mast cell chip; chromatin immunoprecipitation circadian ige mast cells mmcp mouse mouse mast cell protease passive cutaneous anaphylaxis pca per2::luc period2::luciferase sirna small interfering rna the circadian clock zeitgeber time
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    • Forum: Other health news and research
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