pathophysiology

Channelopathies June-Bum Kim Abstract Channelopathies are a heterogeneous group of disorders resulting from the dysfunction of ion channels located in the membranes of all cells and many cellular organelles. These include diseases of the nervous system (e.g., generalized epilepsy with...

Long Covid/Post-Acute-Covid Syndrome as a‘hybrid condition’-A common framework for patients’ experience and pathophysiology AUTHORS Dirk RichterAnastasia Theodoridou Pre-print, accessed December 2021 Abstract While hundreds of thousands of patients suffer from Long Covid/Post-Acute...

Abstract The transient receptor potential (TRP) superfamily of ion channels is involved in the molecular mechanisms that mediate neuroimmune interactions and activities. Recent advancements in neuroimmunology have identified a role for TRP cation channels in several neuroimmune disorders...

(Very unsure where to put this, not quite guidelines, related to ME, but not research either) (Also unsure why it took 2 years to publish this but it's new) Part 1 of 2 (according to this tweet). https://www.sciencedirect.com/science/article/pii/S1566070221000588 Abstract Postural...

Review: A Unifying Hypothesis of the Pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Recognitions from the finding of autoantibodies against ß2-adrenergic receptors KlausWirtha CarmenScheibenbogen...

I found a really interesting comment on the article. https://jamanetwork.com/journals/jama/fullarticle/2737854?resultClick=1#comment-wrapper Someone reports: 1) they themselves have an adrenal condition and they do not think HPA stuff explains ME/CFS (I happen to dislike this theory myself...

Viewpoint Advances in Understanding the Pathophysiology of Chronic Fatigue Syndrome - Anthony L. Komaroff Conclusions A great deal more is known today than 35 years ago about the underlying biology of ME/CFS. It is clear that many biological measurements clearly distinguish patients with...