oxidative stress

Sympathetic Neural Overdrive, Vascular Dysfunction and Diminished Exercise Capacity in Long COVID-19 Patients: A Long-Term Study of Cardiovascular Sequelae Bruna E. Ono; João E. Izaias; Artur O. Sales; Thais S. Rodrigues; Camila S. Nunes; Jessica F. Niec; Natalia G. Rocha; Helena N.M. Rocha...

Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications Semo, Dilvin; Shomanova, Zornitsa; Sindermann, Jürgen; Mohr, Michael; Evers, Georg; Motloch, Lukas J.; Reinecke, Holger; Godfrey, Rinesh; Pistulli, Rudin Cardiovascular...

Dysregulation of lipid metabolism, energy production, and oxidative stress in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Gulf War Syndrome and Fibromyalgia Leah Davis, Maisy Higgs, Ailsa Snaith, Tiffany A Lodge, James Strong, Jose Oltra, Sławomir Kujawski, Pawel Zalewski, Etheresia...

A Comprehensive Review of the Contribution of Mitochondrial DNA Mutations and Dysfunction in Polycystic Ovary Syndrome, Supported by Secondary Database Analysis Kobayashi, Hiroshi; Matsubara, Sho; Yoshimoto, Chiharu; Shigetomi, Hiroshi; Imanaka, Shogo Polycystic ovary syndrome (PCOS) is a...

Proteomic analysis of post-COVID condition: Insights from plasma and pellet blood fractions Alejandro Seco-González, Paula Antelo-Riveiro, Susana B. Bravo, P.F. Garrido, M.J. Domínguez-Santalla, E. Rodríguez-Ruiz, Á. Piñeiro, R. Garcia-Fandino Background Persistent symptoms extending beyond...

Abstract: Objectives Exercise capacity is decreased in diabetes mellitus due to impaired insulin sensitivity, endothelial dysfunction and mitochondrial dysfunction. The aim of the study was to evaluate the effect of metformin on exercise capacity in treatment naïve patients with type 2 diabetes...

ABSTRACT Ethnopharmacological relevance Chronic fatigue syndrome (CFS), as a complex, multisystemic, and multisystemic disorder affecting multiple organs and systems, often accompanies by symptoms such as post-exercise discomfort, sleep disorders, cognitive difficulties, and orthostatic...

It seems cytotoxicity (the ability of a stressor to damage cells) can be a phenomenon that is delayed in comparison to the original stimulus. Ie. it seems depending on the immune or chemical leading to cytotoxicity it can occur instantaneously to a week after. [1] It seems also a well regarded...

Researchers sent engineered heart tissue to the International Space Station and measured how it faired. The study offers a useful means of identifying the molecular pathways behind the detrimental effects of spaceflight on the human heart, says Joseph Wu, a cardiologist at Stanford University...

Neuro-intestinal acetylcholine signalling regulates the mitochondrial stress response in Caenorhabditis elegans Cornell, Rebecca; Cao, Wei; Harradine, Bernie; Godini, Rasoul; Handley, Ava; Pocock, Roger Neurons coordinate inter-tissue protein homeostasis to systemically manage cytotoxic stress...

Increased Oxidative Stress and Decreased Citrulline in Blood Associated with Severe Novel Coronavirus Pneumonia in Adult Patients Tsuge, Mitsuru; Ichihara, Eiki; Hasegawa, Kou; Kudo, Kenichiro; Tanimoto, Yasushi; Nouso, Kazuhiro; Oda, Naohiro; Mitsumune, Sho; Kimura, Goro; Yamada, Haruto...

[Myalgic encephalomyelitis : etiopathogenesis, diagnosis and treatment] (Full article in French) Robin Scherrer, Marian Galovic, Markus Gschwind, Octavia Sabin Published 17 July 2024 Abstract Myalgic encephalomyelitis (ME), also known as chronic fatigue syndrome (CFS), is a neurological...

Endometriosis, Pain, and Related Psychological Disorders: Unveiling the Interplay among the Microbiome, Inflammation, and Oxidative Stress as a Common Thread Cuffaro, Francesca; Russo, Edda; Amedei, Amedeo Endometriosis (EM), a chronic condition in endometrial tissue outside the uterus, affects...

Abstract Background This study investigates the impact of fluctuating lipid levels on endothelial dysfunction. Methods Human aortic and umbilical vein endothelial cells were cultured under varying palmitic acid (PA) concentrations: 0, 50, and 100 μM, and in a variability group alternating...

Oxidative Stress is a shared characteristic of ME/CFS and Long COVID Vishnu Shankar; Julie Wilhelmy; Basil Michael; Layla Cervantes; Vamsee Mallajosyula; Ronald Davis; Michael Snyder; Shady Younis; William H Robinson; Sadasivan Shankar; Paul Mischel; Hector Bonilla; Mark Davis More than 65...

Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches Molnar, Tihamer; Lehoczki, Andrea; Fekete, Monika; Varnai, Reka; Zavori, Laszlo; Erdo-Bonyar, Szabina; Simon, Diana; Berki, Tímea; Csecsei, Peter; Ezer, Erzsebet The COVID-19 pandemic, caused...

Redefining the role of Hypoxia-inducible factors HIFs in oxygen homeostasis Clemente Fernández Arias; Franciso J Acosta; Federica Bertocchini; Cristina Fernández-Arias Hypoxia-inducible factors (HIFs) are key regulators of intracellular oxygen homeostasis. The marked increase in HIFs activity...

Arterial Stiffness and Oxidized LDL Independently Associated With Post-Acute Sequalae of SARS-CoV-2 Sokratis Zisis; Jared Durieux; Christian Mouchati; Nicholas Funderburg; Kate Ailstock; Mary Chong; Danielle Labbato; Grace McComsey Objectives COVID-19 survivors can experience lingering symptoms...

COVID-19 promotes endothelial dysfunction and thrombogenicity: Role of pro-inflammatory cytokines/SGLT2 pro-oxidant pathway Ali Mroueh; Walaa Fakih; Adrien Carmona; Antonin Trimaille; Kensuke Matsushita; Benjamin Marchandot; Abdul Wahid Qureshi; Dal-Seong Gong; Cyril Auger; Laurent Sattler...

Exercise and vascular function in sedentary lifestyles in humans Fasipe, Babatunde; Li, Shunchang; Laher, Ismail People with sedentary lifestyles engage in minimal or no physical activity. A sedentary lifestyle promotes dysregulation of cellular redox balance, diminishes mitochondrial function...