optineurin

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    OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection, 2021, Joshua Ames

    Abstract Fast-replicating neurotropic herpesviruses exemplified by herpes simplex virus-1 (HSV-1) naturally infect the central nervous system (CNS). However, most individuals intrinsically suppress the virus during a primary infection and preclude it from significantly damaging the CNS...
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