objective outcomes

  1. Andy

    Outcome measurement in [FND]: A qualitative study on the views of patients, caregivers & healthcare professionals 2025 Pick et al

    Abstract Background In this qualitative study, we aimed to obtain and synthesise the views of patients with functional neurological disorder (FND), their caregivers, and relevant healthcare professionals (HCPs) on outcome measurement in FND. Methods Semi-structured interviews were conducted...
  2. Sly Saint

    Fatigue and perceived fatigability, not objective fatigability, are prevalent in people with post-COVID-19, 2022 Fietsam et al

    Abstract Persistent symptoms after acute COVID-19 infection, termed post-COVID-19 fatigue, occur in 44–70% of patients. Characterizing fatigue in this population is vital to determine the etiology of post-COVID-19 fatigue symptoms and to assess the effectiveness of potential interventions...
  3. cassava7

    Bias was reduced through the removal of subjective elements from the outcome definition, Kahan et al, 2016

    Bias was reduced in an open-label trial through the removal of subjective elements from the outcome definition Objective: To determine whether modifying an outcome definition to remove subjective elements reduced bias in a trial that could not use blinded outcome assessment. Study design and...
  4. MSEsperanza

    Trials on therapist-delivered treatments (for illnesses or symptoms that don't have biomarkers yet) that used objective outcomes as primary endpoints

    As the title indicates. Looking for examples of such trials. Systematic reviews (*) of trials that excluded (or downgraded to very low quality) non-blinded trials that used only subjective outcomes as primary endpoints also welcome. Suggestions on amendments to the threads' title or topic...
  5. MSEsperanza

    Clinical trial outcome measures of improvement and recovery in ME/CFS - which ones are useful? Discussion thread

    Copied from this thread: Independent advisory group for the full update of the Cochrane review on exercise therapy and ME/CFS (2020), led by Hilda Bastian Leaving some notes here regarding caveats when critiquing most common features of some researchers' claims about trial methodology and...
  6. Andy

    ...discrepancies between objective and subjective measurement of the physical activity level in female patients with [CFS], 2021, Vergauwen et al

    Full title: An exploratory study of discrepancies between objective and subjective measurement of the physical activity level in female patients with chronic fatigue syndrome Highlights • There is a discrepancy between self-report and objective activity measures in CFS. • The activity diary...
  7. MSEsperanza

    Fatigue Exacerbation by Interval or Continuous Exercise in Chronic Fatigue Syndrome (2016) Sandler, C; Llloyd, A; Barry, B

    Sandler, C; Llloyd, A Barry, B (2016), Fatigue Exacerbation by Interval or Continuous Exercise in Chronic Fatigue Syndrome, Medicine & Science in Sports & Exercise: October 2016 - Volume 48 - Issue 10 - p 1875–1885 doi: 10.1249/MSS.0000000000000983 /...
  8. Inara

    Are objective outcomes of cognitive function possible?

    I have a question concerning objective outcomes. Please note I don't mean to not use objective outcomes. How would you measure cognitive function objectively? E.g. my cognitive function improved, but physical function seems to be unchanged. Personally, I value a better cognitive function very...
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