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Cognitive and Neuropsychiatric Sequelae After SARS-CoV-2 Infection: A Narrative Review and Exploratory Cross-Sectional Study of Neurofilament Light Chain and GFAP BACKGROUND Persistent cognitive and neuropsychiatric symptoms have been increasingly reported as part of the post-COVID-19...

Paxlovid shows organ-specific and age-specific impacts on risk of developing post-acute sequelae of COVID-19 BACKGROUND The impact of antiviral therapies, including Paxlovid, on post-acute sequelae of COVID-19 (PASC) remains inconclusive. METHODS We analyzed data from 19,413 patients (age >...

Abstract Background: Neurological Long COVID (n-LC) includes persistent cognitive and autonomic symptoms after SARS-CoV-2 infection. Prior studies of post-COVID conditions have described diverse humoral autoreactivity, but findings are heterogeneous, and it remains unclear whether n-LC is...

A phase 2a double-blind, placebo-controlled randomized trial of the SARS-CoV-2-specific monoclonal antibody AER002 in people with Long COVID Long COVID is a disabling chronic illness with no proven treatments. Persistence of SARS-CoV-2 has been proposed as a biological driver of the disease...

https://www.sciencedirect.com/science/article/abs/pii/S0211563826000015 Fisioterapia Available online 2 March 2026 In Press, Corrected ProofWhat’s this? Original A. Pontes-Silva, M.A. Avila https://doi.org/10.1016/j.ft.2026.01.001Get rights and content Abstract Overview Considering that...

Treatment effects of multimodal inpatient psychotherapy for post-COVID patients: First results from a non-randomized, controlled study BACKGROUND Evidence-based treatment options for post-COVID syndrome remain limited. This study evaluated the effectiveness of a five-week inpatient...

Neither Metformin nor Ursodeoxycholic Acid Effectively Treats Postacute Sequelae of COVID-19 BACKGROUND There is no proven treatment to alleviate symptoms of postacute sequelae of SARS-CoV-2 infection (PASC), despite its substantial public health burden. OBJECTIVE To evaluate the efficacy of...

Exploratory analyses of Immunologic Features in a Randomized, Placebo-Controlled Trial of Nirmatrelvir/Ritonavir for Long COVID This exploratory analysis of PAX LC, a Phase 2, 1:1 randomized, double-blind, superiority, placebo-controlled trial examined whether treatment with...

The causal status of pain catastrophizing: an experimental test with healthy participants Severeijns, Rudy; van den Hout, Marcel A.; Vlaeyen, Johan W.S. Abstract In the current study we report findings on the effects of experimentally induced catastrophizing about pain on expected pain...

Full title: Is long-term disruption of the renin-angiotensin-aldosterone system associated with long COVID? A retrospective cohort study among healthcare workers https://link.springer.com/article/10.1186/s12879-026-12527-z Previous link that required a login...

https://recovercovid.org/news/recover-neuro-clinical-trial-shares-results-three-non-drug-treatments-cognitive-symptoms-long In other words, didn’t work.

Effectiveness of Colchicine for the Treatment of Long COVID: A Randomized Clinical Trial IMPORTANCE Long COVID is characterized by persistent symptoms after SARS-CoV-2 infection, with inflammation playing a key role in pathogenesis. Colchicine, an established anti-inflammatory agent, may...

Preliminary evaluation of a cognitive rehabilitation intervention for post-COVID-19 cognitive impairment: A pilot randomized controlled trial Jacqueline H. Becker, Eric Watson, Nadia Zubair, Fernando Carnavali, Emilia Bagiella, David Reich, Juan P. Wisnivesky Background: Despite the profound...

https://www.degruyterbrill.com/document/doi/10.1515/teb-2025-0017/html Pacing, conventional physical activity and active video gaming to increase physical activity levels for adults with myalgic encephalomyelitis/chronic fatigue syndrome: a pilot feasibility study Brett Tarca , Kade Davison ...

The Effects of a Mindfulness-Based Intervention on Depression and Anxiety in the Long-COVID Population Long-COVID is a complicated, post-viral syndrome involving multiple body systems and can present with neuropsychiatric symptoms. Little has been reported about the neuropsychiatric symptoms...

Abstract Objectives: Fatigue is the main symptom of primary biliary cholangitis (PBC), but has not yet been improved by any therapeutic intervention. This study evaluated the efficacy and safety of hypnosis and psychoeducation in improving fatigue associated with PBC (PBC-HOPE ClinicalTrial.gov...

Effect of normobaric and hyperbaric hyperoxia treatment on symptoms and cognitive capacities in Long COVID patients: a randomised placebo-controlled, prospective, double-blind trial Leen D’hoore, Peter Germonpré, Bert Rinia, Leonard Caeyers, Nancy Stevens, Costantino Balestra [Line breaks...

Now published, see post #4 ------------------------------------ Free: https://www.medrxiv.org/content/10.1101/2024.05.25.24307912v1 Complex Chronic Diseases Program: Program Description & Health Outcomes Assessment from a Clinical Data Registry Emily Meagher, Tianna Magel, Travis Boulter...

Abstract Low-dose naltrexone (LDN) has demonstrated mixed efficacy in treating fibromyalgia. This systematic review and meta-analysis aimed to evaluate the efficacy of LDN for fibromyalgia. We systematically searched electronic databases and gray literature from inception to May 2024. Included...

Ten sessions of hyperbaric oxygen versus sham treatment in patients with long covid HOT-LoCO: a randomised, placebo-controlled, double-blind, phase II trial Anders Kjellberg; Adrian Hassler; Emil Boström; Sara El Gharbi; Sarah Al-Ezerjawi; Anna Schening; Katarina Fischer; Jan H Kowalski; Kenny A...