nad+

  1. SNT Gatchaman

    A missing enzyme-rescue metabolite as cause of a rare skeletal dysplasia, 2025, Jacobs et al.

    A missing enzyme-rescue metabolite as cause of a rare skeletal dysplasia Living cells depend on an intricate network of chemical reactions catalysed by enzymes, which sometimes make mistakes that lead to their inactivation. Here we report a metabolite-based mechanism for preserving enzyme...
  2. forestglip

    Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19, Altay et al, 28 June 2021

    I don't know if Long COVID is the correct forum to put this in, since the study was about recovery from acute COVID. But I think it's possible that something that helps people recover from the acute disease could help with LC. Study
  3. Andy

    The Role of Kynurenine Pathway and NAD + Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2022, Dehhaghi et al

    Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a serious, complex, and highly debilitating long-term illness. People with ME/CFS are typically unable to carry out their routine activities. Key hallmarks of the disease are neurological and gastrointestinal impairments...
  4. leokitten

    The NAD+ Long COVID Theory

    The Team of Doctors and Biohackers Who Seem to Be Successfully Treating “Long Covid” There’s actually quite a number of research papers on this.
  5. Hoopoe

    Increased demand for NAD+ relative to ATP drives aerobic glycolysis, 2020, Luengo et al

    Summary Aerobic glycolysis, or preferential fermentation of glucose-derived pyruvate to lactate despite available oxygen, is associated with proliferation across many organisms and conditions. To better understand that association, we examined the metabolic consequence of activating the pyruvate...
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