muscle biopsy

Daily blood flow restriction does not affect muscle fiber capillarization and satellite cell content during two weeks of bed rest in healthy young men Thorben Aussieker; Cas J. Fuchs; Antoine Zorenc; Lex B. Verdijk; Luc J.C. van Loon; Tim Snijders The present study assessed whether single-leg...

Lipid storage myopathy associated with sertraline treatment is an acquired mitochondrial disorder with respiratory chain deficiency Hedberg-Oldfors, Carola; Lindgren, Ulrika; Visuttijai, Kittichate; Shen, Yan; Ilinca, Andreea; Nordström, Sara; Lindberg, Christopher; Oldfors, Anders Lipid...

KEY POINTS Question: Determine the short- and long-term physical impairments and skeletal muscle cellular changes in survivors of critical COVID. Findings: Survivors of critical COVID have high prevalence of weakness, fatigue, and reduced functional exercise capacity with muscle tissue...

Abstract Post-acute sequelae of COVID (PASC) persist in many patients for weeks and months after recovery from initial SARS-CoV-2 infection. Recent evidence suggests that pathological changes in skeletal muscle may contribute significantly to ongoing pain and fatigue, particularly...

Transcription Profile Analysis of Vastus Lateralis Muscle from Patients with Chronic Fatigue Syndrome T. Pietrangelo; R. Mancinelli; L. Toniolo; G. Montanari; J. Vecchiet; G. Fanò; S. Fulle Chronic fatigue syndrome (CFS) is a disabling condition characterized by unexplained chronic fatigue that...

The Acute, Short-, and Long-Term Effects of Endurance Exercise on Skeletal Muscle Transcriptome Profiles Beiter, Thomas; Zügel, Martina; Hudemann, Jens; Schild, Marius; Fragasso, Annunziata; Burgstahler, Christof; Krüger, Karsten; Mooren, Frank C.; Steinacker, Jürgen M.; Nieß, Andreas M. A...

Functional and Morphological Differences of Muscle Mitochondria in Chronic Fatigue Syndrome and Post-COVID Syndrome Bizjak, Daniel Alexander; Ohmayer, Birgit; Buhl, Jasmine Leonike; Schneider, Elisabeth Marion; Walther, Paul; Calzia, Enrico; Jerg, Achim; Matits, Lynn; Steinacker, Jürgen Michael...

Excessive Intracellular Acidosis Of Skeletal Muscle On Exercise In A Patient With A Post-Viral Exhaustion/Fatigue Syndrome: A 31P Nuclear Magnetic Resonance Study Arnold; Radda; Bore; Styles; Taylor A patient with prolonged post-viral exhaustion and excessive fatigue was examined by 31P nuclear...

Summary We have examined the muscle biopsies of 50 patients who had postviral fatigue syndrome (PFS) for from 1 to 17 years. We found mild to severe atrophy of type II fibres in 39 biopsies, with a mild to moderate excess of lipid. On ultrastructural examination, 35 of these specimens showed...

Structural and functional impairments of skeletal muscle in patients with post-acute sequelae of SARS-CoV-2 infection Marta Colosio ; Lorenza Brocca ; Marco Gatti ; Marianna Neri ; Emanuela Crea ; Francesca Cadile ; Monica Canepari ; Maria Antonietta Pellegrino ; Biagio Polla ; Simone...

The pre-publication thread has been merged with the thread on the paper. Link to paper's abstract here...

Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles Tom Aschman, Emanuel Wyler, Oliver Baum, Andreas Hentschel, Franziska Legler, Corinna Preusse, Lil Meyer-Arndt, Ivana Buettnerova, Alexandra Foerster...

Myopathy as a cause of fatigue in long-term post-COVID-19 symptoms: Evidence of skeletal muscle histopathology Eva K Hejbøl, Thomas Harbo, Jane Agergaard, Line B Madsen, Thomas H Pedersen, Lars J Østergaard, Henning Andersen, Henrik D Schrøder, Hatice Tankisi Background: Among post-COVID-19...

Professor van Vugt: “Just by looking at the muscle biopsies, you see that the firmness of the muscle is different. The firmness of the muscle has to do with the connective tissue, and there are now many theories about that.” My understanding is that the samples have been collected but there...

I came across this paper while looking at a Peter Behan paper from 1985. This paper is from his colleagues using Behan's patients. Abstract Single fibre electromyography (SFEMG) was studied in 40 patients with the post-viral fatigue syndrome. These patients were also assessed clinically...

Note from the moderators: We've copied some posts from a thread where the discussion focussed on the BPS theory of deconditioning to this new thread. ****************************** Hi Everyone My recent muscle biopsy of my thigh has led to what seems like very relevant research findings that...