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mrgprx2
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PACAP activates MRGPRX2 on meningeal mast cells to drive migraine-like pain, 2023, Sbei et al.
PACAP activates MRGPRX2 on meningeal mast cells to drive migraine-like pain Sbei, Sami; Moncrief, Taylor; Limjunyawong, Nathachit; Zeng, Yaping; Green, Dustin P. Migraine ranks among the most prevalent disorders worldwide, leading to disability and decreased quality of life in patients...- SNT Gatchaman
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- headache mast cells meninges migraine mrgprb2 mrgprx2 pain
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- Forum: Other health news and research
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Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome, 2025, Decraecker et al.
Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome Lisse Decraecker; María Cuende Estévez; Samuel Van Remoortel; Runze Quan; Nathalie Stakenborg; Zheng Wang; Elisabetta De Marco; Alexandre Denadai-Souza; Maria Francesca Viola; Sonia Garcia Caraballo; Stuart Brierley; Yasuhiro...- SNT Gatchaman
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- ibs irritable bowel syndrome mast cells mrgprx2 trpv1
- Replies: 1
- Forum: 'Conditions related to ME/CFS' news and research
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Preprint An interorgan neuroimmune circuit promotes visceral hypersensitivity, 2025, Kim+
Abstract: Visceral pain disorders such as interstitial cystitis/bladder pain syndrome (IC/BPS) and irritable bowel syndrome (IBS) often manifest concurrently in the bladder and colon. Yet, the mechanistic basis of such comorbidities and the transmission of neural hypersensitivity across organ...- Nightsong
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- bladder pain syndrome ibs interstitial cystitis irritable bowel syndrome mast cells mrgprb2 mrgprx2 neuroimmune pain visceral hypersensitivity
- Replies: 7
- Forum: Other health news and research