mr spectroscopy

Pilot Study of Peripheral Muscle Function in Primary Biliary Cirrhosis: Potential Implications for Fatigue Pathogenesis BACKGROUND & AIMS Primary biliary cirrhosis (PBC) is characterized in 95% of patients by autoantibody responses directed against the mitochondrial antigen pyruvate...

Abnormalities in pH handling by peripheral muscle and potential regulation by the autonomic nervous system in chronic fatigue syndrome OBJECTIVES To examine muscle acid handling following exercise in chronic fatigue syndrome (CFS⁄ME) and the relationship with autonomic dysfunction. DESIGN...

Loss of capacity to recover from acidosis in repeat exercise is strongly associated with fatigue in primary biliary cirrhosis BACKGROUND & AIMS Upon exercise, primary biliary cirrhosis (PBC) is associated with significant acidosis in peripheral muscle with recovery rate from acidosis strongly...

Loss of capacity to recover from acidosis on repeat exercise in chronic fatigue syndrome: a case–control study BACKGROUND Chronic fatigue syndrome (CFS) patients frequently describe difficulties with repeat exercise. Here, we explore muscle bioenergetic function in response to three bouts of...

Creatine kinase imaging CKI for in vivo whole-brain mapping of creatine kinase reaction kinetics The creatine kinase (CK) is a key enzyme involved in brain bioenergetics, playing an important role in brain function and the pathogenesis of neurological and psychiatric diseases and cancers...

Magnetic Resonance Quantification of Muscle Phosphocreatine Resynthesis Kinetics During Exercise Recovery: An In Vivo Measure of Mitochondrial Function in Humans Quantifying muscle phosphocreatine (PCr) resynthesis kinetics during recovery from exercise can be employed as a sensitive and...

Neurometabolic network NMetNet for functional neurological disorder in children and adolescents Lan; Foster; Charney; Grinsven; Breedlove; Kozlowska; Lin OBJECTIVES Functional neurological disorder (FND) in children and adolescents is a biopsychosocially-complex condition characterized by a...

https://www.mdpi.com/1648-9144/60/8/1370 A Multimodal Magnetic Resonance Imaging Study on Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: Feasibility and Clinical Correlation Abstract Background/Objectives: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a neurological...

Decreased Cerebral Creatine and N-Acetyl Aspartate Concentrations after Severe COVID-19 Infection: A Magnetic Resonance Spectroscopy Study Ostojic, Jelena; Kozic, Dusko; Ostojic, Sergej; Ilic, Aleksandra DJ; Galic, Vladimir; Matijasevic, Jovan; Dragicevic, Dusan; Barak, Otto; Boban, Jasmina...

Metabolic changes assessed by 1H MR spectroscopy in the corpus callosum of post-COVID patients Pajuelo, Dita; Dezortova, Monika; Hajek, Milan; Ibrahimova, Marketa; Ibrahim, Ibrahim OBJECTIVES Many patients with long COVID experience neurological and psychological symptoms. Signal abnormalities...

Brain temperature and free water increases after mild COVID-19 infection Sharma, Ayushe A.; Nenert, Rodolphe; Goodman, Adam M.; Szaflarski, Jerzy P. The pathophysiology underlying the post-acute sequelae of COVID-19 remains understudied and poorly understood, particularly in healthy adults with...

Excessive Intracellular Acidosis Of Skeletal Muscle On Exercise In A Patient With A Post-Viral Exhaustion/Fatigue Syndrome: A 31P Nuclear Magnetic Resonance Study Arnold; Radda; Bore; Styles; Taylor A patient with prolonged post-viral exhaustion and excessive fatigue was examined by 31P nuclear...

Reduced Oxygen Extraction Fraction in Deep Cerebral Veins Associated with Cognitive Impairment in Multiple Sclerosis Hasan Sawan; Chenyang Li; Sagar Buch; Evanthia Bernitsas; Ewart Mark Haacke; Yulin Ge; Yongsheng Chen Studying the relationship between cerebral oxygen utilization and cognitive...

Ventricular cerebrospinal fluid lactate is increased in chronic fatigue syndrome compared with generalized anxiety disorder: an in vivo 3.0 T 1H MRS imaging study Sanjay J. Mathew; Xiangling Mao; Kathryn A. Keegan; Susan M. Levine; Eric L. P. Smith; Linda A. Heier; Viktor Otcheretko; Jeremy D...

Cortical GABA Levels Are Reduced in Post-Acute COVID-19 Syndrome Marinkovic, Ksenija; White, David R.; Alderson Myers, Austin; Parker, Katie S.; Arienzo, Donatello; Mason, Graeme F. After recovering from the acute COVID-19 illness, a substantial proportion of people continue experiencing...

Neurometabolic Alterations in Children and Adolescents with Functional Neurological Disorder Charney; Foster; Shukla; Zhao; Jiang; Kozlowska; Lin Objectives In vivo magnetic resonance spectroscopy (MRS) was used to investigate neurometabolic homeostasis in children with functional neurological...

Impaired oxygen delivery to muscle in chronic fatigue syndrome McCully, Kevin K.; Natelson, Benjamin H. The purpose of this study was to determine if chronic fatigue syndrome (CFS) is associated with reduced oxygen delivery to muscles. Patients with CFS according to CDC (Center for Disease...

Extensive Brain Pathologic Alterations Detected with 7.0-T MR Spectroscopic Imaging Associated with Disability in Multiple Sclerosis Eva Heckova; Assunta Dal-Bianco; Bernhard Strasser; Gilbert J. Hangel; Alexandra Lipka; Stanislav Motyka; Lukas Hingerl; Paulus S. Rommer; Thomas Berger; Petra...

Note that this is a study from 1998 and is posted for potential future reference. Abstract It has been shown previously that some patients with chronic fatigue syndrome show an abnormal increase in plasma lactate following a short period of moderate exercise, in the sub-anaerobic threshold...