microglial activation

Inflammation from mild COVID-19 results in persistent neurological and behavioral changes in rhesus macaques Although most SARS-CoV-2 infections result in mild or moderate symptoms not requiring hospitalization, many patients experience persistent symptoms after their initial recovery, a...

Microglial Activation in Nociplastic Pain: From Preclinical Models to PET Neuroimaging and Implications for Targeted Therapeutic Strategies Nociplastic pain has recently been introduced as a third entity for identifying patients suffering from chronic pain that arises from altered nociception...

Underlying cause of Gulf War illness confirmed Link to research: Decadelong low basal ganglia NAA/tCr from elevated tCr supports ATP depletion from mitochondrial dysfunction and neuroinflammation in Gulf War illness

Crosstalk Among Disrupted Blood-Brain Barrier, Neuroinflammation, and Coagulopathy in AC70 hACE2 Tg Mice with Prolonged Neurological Manifestations Induced by the Omicron BA.1 Variant of SARS-CoV-2 Aleksandra K Drelich; Panatda Saenkham-Huntsinger; Yu-Hsiu E. Wang; Xuping Xie; Barbara M. Judy...

Long COVID elevated MMP-9 and release from microglia by SARS-CoV-2 Spike protein Duraisamy Kempuraj; Irene Tsilioni; Kristina K. Aenlle; Nancy G. Klimas; Theoharis C. Theoharides OBJECTIVES Long COVID is a major health concern because many patients develop chronic neuropsychiatric symptoms, but...

The S1 subunits of SARS-CoV-2 variants differentially trigger the IL-6 signaling pathway in human brain endothelial cells and downstream impact on microglia activation Michael Stangis; Daniel Adesse; Bhavya Sharma; Eduardo Castro; Kush Kumar; Neil Kumar; Masha Minevich; Michal Toborek...

The Human Microglia Atlas HuMicA Unravels Changes in Homeostatic and Disease-Associated Microglia Subsets across Neurodegenerative Conditions Ricardo Martins-Ferreira; Josep Calafell-Segura; Barbara Leal; Javier Rodriguez-Ubreva; Elisabetta Mereu; Paulo Pinho e Costa; Esteban Ballestar...