macrophages

  1. forestglip

    Hypothesis Perspective: host factors variants and the underlying causes of long COVID, 2025, Pasharawipas

    Perspective: host factors variants and the underlying causes of long COVID Tirasak Pasharawipas Long COVID, also known as post-COVID syndrome (PCS), is characterized by persistent and unexplained symptoms that can occur not only in individuals who experienced severe symptoms during the acute...
  2. Jonathan Edwards

    Notice about a forthcoming paper: A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma

    Link to the thread on the preprint - 27 May 2025: A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma, 2025, Edwards, Cambridge and Cliff ****** I am hoping that the paper I have been writing with Jo Cambridge and Jackie Cliff will appear on Qeios tomorrow. If...
  3. jnmaciuch

    Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation, 2020, Seim et al.

    Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation Gretchen L Seim, Emily C Britt, Steven V John, Franklin J Yeo, Aaron R Johnson, Richard S Eisenstein, David J Pagliarini, Jing Fan Abstract In response to signals associated with...
  4. jnmaciuch

    Malate initiates a proton-sensing pathway essential for pH regulation of inflammation, 2024, Chen et al.

    Malate initiates a proton-sensing pathway essential for pH regulation of inflammation Yu-jia-nan Chen, Rong-chen Shi, Yuan-cai Xiang, Li Fan, Hong Tang, Gang He, Mei Zhou, Xin-zhe Feng, Jin-dong Tan, Pan Huang, Xiao Ye, Kun Zhao, Wen-yu Fu, Liu-li Li, Xu-ting Bian, Huan Chen, Feng Wang, Teng...
  5. jnmaciuch

    Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages, 2018, Wang et al.

    Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity Feilong Wang ∙ Song Zhang ∙ Ryounghoon Jeon ∙ Ivan Vuckovic ∙ Xintong Jiang∙ Amir Lerman∙ Clifford D. Folmes ∙ Petras D. Dzeja ∙ Joerg Herrmann Highlights...
  6. Mij

    Itaconate modulates immune responses via inhibition of peroxiredoxin 5, 2025, Tomas Paulenda et al

    Abstract The immunoregulatory metabolite itaconate accumulates in innate immune cells upon Toll-like receptor stimulation. In response to macrophage activation by lipopolysaccharide, itaconate inhibits inflammasome activation and boosts type I interferon signalling; however, the molecular...
  7. SNT Gatchaman

    Neutrophil extracellular traps and macrophage activation [contribute] to thrombosis and post-covid syndrome […], 2025, Serrano-Gonzalo+

    Neutrophil extracellular traps and macrophage activation contibute to thrombosis and post-covid syndrome in SARS-CoV-2 infection Serrano-Gonzalo, Irene; Menéndez-Jandula, Bárbara; Franco-García, Esther; Arévalo-Vargas, Isidro; Lahoz-Gil, Calos; Latre, Paz; Roca-Esteve, Sonia; Köhler, Ralf; López...
  8. forestglip

    340 – Monocyte Dysregulation in PASC With Ongoing Pulmonary Symptoms, 2025, Awamura et al

    340 – Monocyte Dysregulation in PASC With Ongoing Pulmonary Symptoms Thomas K. Awamura, Stefanos Giannakopoulos, Dominic C. Chow, Cecilia M. Shikuma, Gehan Devendra, Vedbar Khadka, Juwon Park Background As the number of COVID-19 survivors amongst the global population continues to rise, the...
    • forestglip
    • Thread
    • chronic inflammatory disorder il-10 il-6 il-8 inflammation interstitial pneumonia long covid macrophages monocytes neutrophils nitric oxide reactive oxygen species vasculitis
    • Replies: 1
    • Forum: Long Covid research
  9. forestglip

    Thesis Clinical, histopathological, and radiological characterization of post-acute sequelae of COVID-19, 2025, Czech

    Clinical, histopathological, and radiological characterization of post-acute sequelae of COVID-19 Anna Czech Abstract Numerous patients exhibit enduring symptoms following a Coronavirus Disease 2019 (COVID-19) infection, termed Post-Acute Sequelae of COVID-19 (PASC). The typical manifestations...
    • forestglip
    • Thread
    • cd4+ fev1 fibrinous alveolitis forced vital capacity il-1b lav long covid macrophages organizing pneumonia oxygen pulse t cells viral persistence
    • Replies: 0
    • Forum: Long Covid research
  10. SNT Gatchaman

    Polymerized Type I Collagen Downregulates STAT-1 Phosphorylation Through Engagement with LAIR-1 in Monocytes, Avoiding [LC], 2025, Olivares-Martínez+

    Polymerized Type I Collagen Downregulates STAT-1 Phosphorylation Through Engagement with LAIR-1 in Circulating Monocytes, Avoiding Long COVID Olivares-Martínez, Elizabeth; Hernández-Ramírez, Diego Francisco; Núñez-Álvarez, Carlos Alberto; Meza-Sánchez, David Eduardo; Chapa, Mónica...
  11. SNT Gatchaman

    Exercise intensity and training alter the innate immune cell type and chromosomal origins of circulating cell-free DNA in humans, 2025, Rodrigues+

    Exercise intensity and training alter the innate immune cell type and chromosomal origins of circulating cell-free DNA in humans Rodrigues, Kameron B.; Weng, Ziming; Graham, Zachary A.; Lavin, Kaleen; McAdam, Jeremy; Tuggle, S. Craig; Peoples, Brandon; Seay, Regina; Yang, Sufen; Bamman, Marcas...
  12. Mij

    Persistent Fatigue, Weakness, and Aberrant Muscle Mitochondria in Survivors of Critical COVID-19, 2024, Kirby P Mayer et al

    KEY POINTS Question: Determine the short- and long-term physical impairments and skeletal muscle cellular changes in survivors of critical COVID. Findings: Survivors of critical COVID have high prevalence of weakness, fatigue, and reduced functional exercise capacity with muscle tissue...
    • Mij
    • Thread
    • cd206 cytochrome c oxidase intensive care macrophages mitochondria muscle muscle biopsy muscle fibre
    • Replies: 2
    • Forum: Long Covid research
  13. SNT Gatchaman

    An aberrant immune–epithelial progenitor niche drives viral lung sequelae, 2024, Narasimhan et al.

    An aberrant immune–epithelial progenitor niche drives viral lung sequelae Narasimhan, Harish; Cheon, In Su; Qian, Wei; Hu, Sheng’en Shawn; Parimon, Tanyalak; Li, Chaofan; Goplen, Nick; Wu, Yue; Wei, Xiaoqin; Son, Young Min; Fink, Elizabeth; de Almeida Santos, Gislane; Tang, Jinyi; Yao, Changfu...
  14. SNT Gatchaman

    The choroid plexus synergizes with immune cells during neuroinflammation, 2024, Xu et al.

    The choroid plexus synergizes with immune cells during neuroinflammation Huixin Xu; Peter Lotfy; Sivan Gelb; Aja Pragana; Christine Hehnly; Lillian I.J. Byer; Frederick B. Shipley; Miriam E. Zawadzki; Jin Cui; Liwen Deng; Milo Taylor; Mya Webb; Hart G.W. Lidov; Mark L. Andermann; Isaac M. Chiu...
    • SNT Gatchaman
    • Thread
    • blood brain barrier blood csf barrier cerebrospinal fluid choroid plexus immune system innate immune response macrophages monocytes neuroinflammation neutrophils
    • Replies: 1
    • Forum: Other health news and research
  15. SNT Gatchaman

    Preprint Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19, 2024, Ashok et al.

    Innate Immune Activation and Mitochondrial ROS Invoke Persistent Cardiac Conduction System Dysfunction after COVID-19 Deepthi Ashok; Ting Liu; Joseph Criscione; Meghana Prakash; Byunggik Kim; Julian Chow; Morgan Craney; Kyriakos Papanicolaou; Agnieszka Sidor; D. Brian Foster; Andrew Pekosz...
    • SNT Gatchaman
    • Thread
    • arrhythmia cardiac cardiac function cytokines innate immune response interferon interferon-stimulated genes jak inhibitors jak-stat macrophages mitochondria reactive oxygen species
    • Replies: 0
    • Forum: Long Covid research
  16. SNT Gatchaman

    Macrophage SREBP1 regulates skeletal muscle regeneration, 2024, Oishi et al.

    Macrophage SREBP1 regulates skeletal muscle regeneration Oishi, Yumiko; Koike, Hiroyuki; Kumagami, Naoki; Nakagawa, Yoshimi; Araki, Masaya; Taketomi, Yoshitaka; Miki, Yoshimi; Matsuda, Shigeru; Matsuzaka, Takashi; Ozawa, Hitoshi; Shimano, Hitoshi; Murakami, Makoto; Manabe, Ichiro Macrophages...
  17. Mij

    Single-cell RNA-Seq reveals intracellular microbial diversity within immune cells during SARS-CoV-2 infection and recovery, 2023, Sunita Yadav et al

    Highlights 76 bacterial species of 15 genera across healthy, COVID-19-positive, and recovered individuals Higher abundance of opportunistic intracellular bacteria in recovered group Higher microbial abundance within antigen-presenting cells of COVID-19 patients Differential microbial abundance...
    • Mij
    • Thread
    • b cells covid dendritic cells innate immune response intracellular infection intracellular pathogen macrophages monocytes nk cells pbmc plasma cells platelets single-cell transcriptomics t cells
    • Replies: 6
    • Forum: Epidemics (including Covid-19, not Long Covid)
  18. SNT Gatchaman

    Preprint Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications, 2023, Mikulski et al.

    Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications Pawel Mikulski; Sahar S.H. Tehrani; Anna Kogan; Izma Abdul-Zani; Emer Shell; Brent J Ryan; Lars E.T. Jansen Interferon-γ (IFNγ) transiently activates genes involved in...
  19. SNT Gatchaman

    Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis, 2023, Wang et al.

    Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis Jue Wang; Shiva Keshava; Kaushik Das; Richard Kolesnick; Xian-Cheng Jiang; Usha R. Pendurthi; L. Vijaya Mohan Rao BACKGROUND: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue...
  20. E

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells, 2023, Huot et al

    SARS-CoV-2 viral persistence in lung alveolar macrophages is controlled by IFN-γ and NK cells Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA generally becomes undetectable in upper airways after a few days or weeks postinfection. Here we used a model of viral...
    • EndME
    • Thread
    • animal study fibronectin interferon interferon-y lungs macrophages nk cells t cells viral persistence
    • Replies: 4
    • Forum: Long Covid research
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