lysosomes

  1. SNT Gatchaman

    [Preprint] TGF-β inhibitor SB431542 suppresses coronavirus replication through multistep inhibition, 2025, Verma et al.

    TGF-β inhibitor SB431542 suppresses coronavirus replication through multistep inhibition Assim Verma; Garvit Kumar; Nitin Khandelwal; Benjamin E Mayer; Jitender Rathee; Yogesh Chander; Alka Nokhwal; Shweta Dhanda; Ram Kumar; Himanshu Kamboj; Riyesh Thachamvally; Shalini Sharma; Naveen Kumar The...
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    Preprint Chloride Homeostasis Regulates cGAS-STING Signaling, 2024, Morse et al.

    Chloride Homeostasis Regulates cGAS-STING Signaling Jared Morse; Danna Wang; Serena Mei; Danielle Whitham; Colby Hladun; Costel C. Darie; Herman O Sintim; Modi Wang; KaHo Leung The cGAS-STING signaling pathway has emerged as a key mediator of inflammation. However, the roles of chloride...
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    Fatigue as hallmark of Fabry disease: role of bioenergetic alterations 2024 Gambardella et al

    Fabry disease (FD) is a lysosomal storage disorder due to the impaired activity of the α-galactosidase A (GLA) enzyme which induces Gb3 deposition and multiorgan dysfunction. Exercise intolerance and fatigue are frequent and early findings in FD patients, representing a self-standing clinical...
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    A genetically modulated Toll-like-receptor-tolerant phenotype in peripheral blood cells of children with multisystem inflammatory syndrome, 2024, Khan

    A genetically modulated Toll-like-receptor-tolerant phenotype in peripheral blood cells of children with multisystem inflammatory syndrome. Rehan Khan; Weizhen Ji; Jeisac Guzman-Rivera; Abhilasha Madhvi; Tracy Andrews; Benjamin Richlin; Christian Suarez; Sunanda Gaur; William Cuddy; Aalok R...
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    • children gut permeability innate immune response khan long covid lysosomes mis-c mitochondria zonulin
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    • Forum: Long Covid research
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    Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs, 2021, Todkar et al.

    Selective packaging of mitochondrial proteins into extracellular vesicles prevents the release of mitochondrial DAMPs Todkar, Kiran; Chikhi, Lilia; Desjardins, Véronique; El-Mortada, Firas; Pépin, Geneviève; Germain, Marc Most cells constitutively secrete mitochondrial DNA and proteins in...
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    Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired, 2023, Liang et al.

    Mitochondria are secreted in extracellular vesicles when lysosomal function is impaired Liang, Wenjing; Sagar, Shakti; Ravindran, Rishith; Najor, Rita H.; Quiles, Justin M.; Chi, Liguo; Diao, Rachel Y.; Woodall, Benjamin P.; Leon, Leonardo J.; Zumaya, Erika; Duran, Jason; Cauvi, David M.; De...
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