lymphatics

Lymphatic dysfunction is linked to disease pathogenesis in Duchenne muscular dystrophy animal models Duchenne muscular dystrophy (DMD) is a severe muscle-wasting disorder characterized by progressive muscle weakness and inflammation caused by mutations in the DMD gene. Chronic inflammation in...

Meningeal lymphatics-microglia axis regulates synaptic physiology Kyungdeok Kim; Daviti Abramishvili; Siling Du; Zachary Papadopoulos; Jay Cao; Jasmin Herz; Igor Smirnov; Jean-Leon Thomas; Marco Colonna; Jonathan Kipnis SUMMARY Meningeal lymphatics serve as an outlet for cerebrospinal fluid...

Evidence for cellular and solute passage between the brain and skull bone marrow across meninges: A systematic review Helena Eide Therkelsen; Rune Enger; Per Kristian Eide; Geir Ringstad A potential two-way passage of cells and substances between the brain and skull bone marrow may open for new...

YouTube Explanation: Link to Figures: https://docs.google.com/document/d/1Dwanor7_78l0Wej1DgYcCy0aScdKruimfGi4IObEmSo/edit?usp=sharing Environmental science is an area of critical importance that is frequently overlooked in medical research, despite the environment’s disproportionately large...

The Glymphatic System: A Beginner’s Guide Jessen, Nadia Aalling; Munk, Anne Sofie Finmann; Lundgaard, Iben; Nedergaard, Maiken The glymphatic system is a recently discovered macroscopic waste clearance system that utilizes a unique system of perivascular tunnels, formed by astroglial cells, to...

Brain borders at the central stage of neuroimmunology Rustenhoven, Justin; Kipnis, Jonathan The concept of immune privilege suggests that the central nervous system is isolated from the immune system. However, recent studies have highlighted the borders of the central nervous system as central...