lipid metabolism

Proteomic and metabolomic profiling of plasma uncovers immune responses in patients with Long COVID-19 Yulin Wei, Hongyan Gu, Jun Ma, Xiaojuan Mao, Bing Wang, Weiyan Wu, Shimin Yu, Jinyuan Wang, Huan Zhao, yanbin he [Preprint] Abstract Long COVID is an often-debilitating condition with...

Long-term dysregulation of plasma peptidome in mild and multiple COVID-19 recovered patients revealed by a novel efficient peptidomics workflow Song, Zhijing; Liu, Chaoran; Liu, Yaozhou; Bian, Zheng; Sun, Qing; He, Ting; Su, Rong; Huang, Shengchun; Dai, Ningbin; Zhao, Ke li; Li, Yan; Liang, Kai...

Lipid storage myopathy associated with sertraline treatment is an acquired mitochondrial disorder with respiratory chain deficiency Hedberg-Oldfors, Carola; Lindgren, Ulrika; Visuttijai, Kittichate; Shen, Yan; Ilinca, Andreea; Nordström, Sara; Lindberg, Christopher; Oldfors, Anders Lipid...

Chronic Viral Reactivation and Associated Host Immune Response and Clinical Outcomes in Acute COVID-19 and Post-Acute Sequelae of COVID-19 Chronic viral infections are ubiquitous in humans, with individuals harboring multiple latent viruses that can reactivate during acute illnesses. Recent...

A six-year study in a real-world population reveals an increased incidence of dyslipidemia during COVID-19 Valentina Trimarco; Raffaele Izzo; Stanislovas S. Jankauskas; Mario Fordellone; Giuseppe Signoriello; Maria Virginia Manzi; Maria Lembo; Paola Gallo; Giovanni Esposito; Roberto Piccinocchi...

Abstract Vitamin D, a crucial hormone in the homeostasis and metabolism of calcium bone, has lately been found to produce effects on other physiological and pathological processes genomically and non-genomically, including the cardiovascular system. While lower baseline vitamin D levels have...

Gunasekaran Ramanathan Background: Earlier studies have suggested that Sunlight and vitamin D are related to cardiovascular disease (CVD), but the link between sunlight exposure and risk factors for CVD has not been adequately investigated. Dyslipidaemia is a major risk factor for CVD we aim to...

Specific activation of the integrated stress response uncovers regulation of central carbon metabolism and lipid droplet biogenesis Labbé, Katherine; LeBon, Lauren; King, Bryan; Vu, Ngoc; Stoops, Emily H.; Ly, Nina; Lefebvre, Austin E. Y. T.; Seitzer, Phillip; Krishnan, Swathi; Heo, Jin-Mi...

Spaceflight alters host-gut microbiota interactions Gonzalez, E.; Lee, M. D.; Tierney, B. T.; Lipieta, N.; Flores, P.; Mishra, M.; Beckett, L.; Finkelstein, A.; Mo, A.; Walton, P.; Karouia, F.; Barker, R.; Jansen, R. J.; Green, S. J.; Weging, S.; Kelliher, J.; Singh, N. K.; Bezdan, D.; Galazska...

The germline coordinates mitokine signaling Koning Shen; Jenni Durieux; Cesar G. Mena; Brant M. Webster; C. Kimberly Tsui; Hanlin Zhang; Larry Joe; Kristen M. Berendzen; Andrew Dillin The ability of mitochondria to coordinate stress responses across tissues is critical for health. In C...

Quantitative imaging of species-specific lipid transport in mammalian cells Juan M. Iglesias-Artola; Kai Schumann; Kristin Bohlig; H. Mathilda Lennartz; Milena Schumacher; Pavel Barahtjan; Cristina Jiminez Lopez; Radek Sachl; Karina Pombo-Garcia; Annett Lohmann; Petra Riegerova; Martin Hof...

Abstract Background This study investigates the impact of fluctuating lipid levels on endothelial dysfunction. Methods Human aortic and umbilical vein endothelial cells were cultured under varying palmitic acid (PA) concentrations: 0, 50, and 100 μM, and in a variability group alternating...

Subcellular imaging of lipids and sugars using genetically encoded proximity sensors William M. Moore; Roberto J. Brea; Caroline Knittel; Ellen Wrightsman; Brandon Hui; Jinchao Loui; Christelle F. Ancajas; Michael D. Best; Neal K. Devaraj; Itay Budin Live cell imaging of lipids and other...

Lipidomics signature in post-COVID patient sera and its influence on the prolonged inflammatory response Abstract Background: The ongoing issues with post-COVID conditions (PCC), where symptoms persist long after the initial infection, highlight the need for research into blood lipid changes...

The role of Sphingolipids in myelination and myelin stability and their involvement in childhood and adult demyelinating disorders Paola Giussani; Alessandro Prinetti; Cristina Tringali Multiple sclerosis (MS) represents the most common demyelinating disease affecting the central nervous system...

Sphingolipids and their metabolism in physiology and disease Hannun, Yusuf A.; Obeid, Lina M. Studies of bioactive lipids in general and sphingolipids in particular have intensified over the past several years, revealing an unprecedented and unanticipated complexity of the lipidome and its many...

Proteomic Evolution from Acute to Post-COVID-19 Conditions Yassene Mohammed; Karen Tran; Chris Carlsten; Christopher Ryerson; Alyson Wong; Terry Lee; Matthew P. Cheng; Donald C. Vinh; Todd C. Lee; Brent W. Winston; David Sweet; John H. Boyd; Keith R. Walley; Greg Haljan; Allison McGeer; Francois...

Tale of two systems: the intertwining duality of fibrinolysis and lipoprotein metabolism Wen Dai; Mark Castleberry; Ze Zheng Fibrinolysis is an enzymatic process that breaks down fibrin clots, while dyslipidemia refers to abnormal levels of lipids and lipoproteins in the blood. Both...

Circulating Metabolome and White Matter Hyperintensities in Women and Men Eeva Sliz; Jean Shin; Shahzad Ahmad; Dylan M. Williams; Stefan Frenzel; Friederike Gauß; Sarah E. Harris; Ann-Kristin Henning; Maria Valdes Hernandez; Yi-Han Hu; Beatriz Jiménez; Muralidharan Sargurupremraj; Carole Sudre...

Full Title: Dysregulations in hemostasis, metabolism, immune response, and angiogenesis in post-acute COVID-19 with and without POTS syndrome; a multi-omic profiling study, 2023, Ali Mahdi et al Abstract Post-acute COVID-19 (PACS) are associated with cardiovascular dysfunction, especially...