ketamine

Clinical treatment of cluster headache with the serotonergic indoleamine psychedelics psilocybin and LSD and with ketamine: A case series Jonathan Leighton, Carmen Lau, Aisha Savdo, Livia Granata Background Cluster headache is an excruciating condition for which standard treatments are usually...

Abstract The accumulation of metabolic waste is a leading cause of numerous neurological disorders, yet we still have only limited knowledge of how the brain performs self-cleansing. Here we demonstrate that neural networks synchronize individual action potentials to create large-amplitude...

A unified model of ketamine’s dissociative and psychedelic properties Miriam Marguilho, Inês Figueiredo, and Pedro Castro-Rodrigues Abstract Ketamine is an N-methyl-d-aspartate antagonist which is increasingly being researched and used as a treatment for depression. In low doses, it can...

After an appeal by Janssen (the pharmaceutical company that manufactures esketamine) in July, NICE reviewed the evidence they submitted again in a technology appraisal guidance (TAG) and recommended against its use for treatment-resistant depression. The TAG committee’s discussion is an...

Abstract Background Fibromyalgia is a chronic multidimensional pain disease with no curative treatment currently available. Its management relies on a multimodal approach involving pharmacologic and non-pharmacologic elements. Because a suggested factor in its etiology is a central...

full details https://www.cc.nih.gov/sites/nihinternet/files/internet-files/recruit/pdfs/20_fatigue.pdf (this pdf seems to have been created last year?)

https://www.neurologyadvisor.com/topics/multiple-sclerosis/the-role-of-ketamine-infusion-for-patients-with-ms-related-fatigue/ Primary outcome of the study was negative. Reference Fitzgerald KC, Morris B, Soroosh A, et al. Pilot randomized active-placebo-controlled trial of low-dose ketamine...

Popular article https://multiplesclerosisnewstoday.com/news-posts/2020/07/07/pilot-randomized-active-placebo-controlled-trial-of-low-dose-ketamine-for-the-treatment-of-multiple-sclerosisrelated-fatigue/ Journal https://journals.sagepub.com/doi/abs/10.1177/1352458520936226?journalCode=msja

I thought this was generally interesting, shedding some light, as it does, on how ketamine and psychedelics affect the brain structurally, and suggesting the possibility of new drugs for depression and anxiety based on these chemicals. Ketamine was also suggested and tried as a treatment for ME...