Abstract:
Evidence bearing on possible mechanisms for the clinical syndrome of ME/CFS is reviewed. The evidence is used to argue for a hypothesis that centres on a form of persistent, inappropriate, ‘neuroimmune hypervigilance’ mediated primarily by T lymphocyte-macrophage interaction but...
Link to the thread on the preprint - 27 May 2025:
A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma, 2025, Edwards, Cambridge and Cliff
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I am hoping that the paper I have been writing with Jo Cambridge and Jackie Cliff will appear on Qeios tomorrow. If...
Management of Nutritional Failure in People with Severe ME/CFS: Review of the Case for Supplementing NICE Guideline NG206 (preprint)
@Jonathan Edwards
Abstract:
In the United Kingdom, a small but steady stream of people diagnosed with ME/CFS (myalgic encephalomyelitis/chronic fatigue syndrome)...
Edwards JC, McGrath S, Baldwin A, Livingstone M, Kewley A. The biological challenge of myalgic encephalomyelitis/chronic fatigue syndrome: a solvable problem. Fatigue. 2016;4(2):63-69. doi:10.1080/21641846.2016.1160598
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4867862/
Abstract
Myalgic...
Thought it could be helpful to have a thread on Jonathan's expert testimony for any further use and citation.
Edwards, Jonathan CW (2020), The difficulties of conducting intervention trials for the treatment of myalgic encephalomyelitis/chronic fatigue syndrome: Expert testimony presented to...
Interesting article I had not seen before; features Len Jason, PACE trial, David Tuller, Mary Dimmock, Wessely, White, Esther Crawley, Steven Holgate, Jo Edwards and more.
just pop this bit in here
o_O
https://goodmenproject.com/the-good-life/worklife-balance/fighting-over-fatigue/
Professor Edwards' Letter to MRC's Fiona Watt
Professor Edwards signed the open letter to The Lancet. He originally wrote his own letter to Professor Watt in confidence. Since she has now strongly endorsed PACE in her letter to The Times, he has given me permission to post what he wrote.
This post and subsequent discussion have been moved from this thread.
For no particular reason I am posting here a document that will be made public by the Scottish Parliament in support of @Emsho's petition.
Screening being held at the London School of Hygiene and Tropical Medicine tonight with a livestreamed Q&A afterwards with Dr Charles Shepherd and Prof @Jonathan Edwards
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