inflammasome

  1. chillier

    The human disease-associated gene ZNFX1 controls inflammation through inhibition of the NLRP3 inflammasome, 2024, Huang et al

    Abstract Inherited deficiency of zinc finger NFX1-type containing 1 (ZNFX1), a dsRNA virus sensor, is associated with severe familial immunodeficiency, multisystem inflammatory disease, increased susceptibility to viruses, and early mortality. However, limited treatments for patients with...
  2. SNT Gatchaman

    Mast cells boost anti-tumor potency of MAIT cells via inflammasome-dependent secretion of IL-18, 2025, Fan et al.

    Mast cells boost anti-tumor potency of MAIT cells via inflammasome-dependent secretion of IL-18 Fan, Fanfan; Wang, Jun; Liu, Kun; Zhang, Shiyue; Gao, Jian; Li, Xiongfei; Ma, Jiaqiang; Zhao, Yue; Li, Teng; Su, Han; Yang, Xinfeng; Han, Han; Huang, Qingyuan; Zhang, Yiliang; Pan, Yunjian; Ye, Ting...
  3. SNT Gatchaman

    Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications, 2025, Semo+

    Persistent Monocytic Bioenergetic Impairment and Mitochondrial DNA Damage in PASC Patients with Cardiovascular Complications Semo, Dilvin; Shomanova, Zornitsa; Sindermann, Jürgen; Mohr, Michael; Evers, Georg; Motloch, Lukas J.; Reinecke, Holger; Godfrey, Rinesh; Pistulli, Rudin Cardiovascular...
    • SNT Gatchaman
    • Thread
    • caspase caspase-1 glutathione grp78 il-1b immunoparalysis inflammasome mitochochria monocytes mtdna oxidative stress reactive oxygen species seahorse tlr-4 tlr-9
    • Replies: 2
    • Forum: Long Covid research
  4. SNT Gatchaman

    Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis, 2022, Eltobgy, Amer et al.

    Caspase-4/11 exacerbates disease severity in SARS–CoV-2 infection by promoting inflammation and immunothrombosis Eltobgy, Mostafa M.; Zani, Ashley; Kenney, Adam D.; Estfanous, Shady; Kim, Eunsoo; Badr, Asmaa; Carafice, Cierra; Daily, Kylene; Whitham, Owen; Pietrzak, Maciej; Webb, Amy; Kawahara...
  5. SNT Gatchaman

    Preprint Persistent immune dysregulation and metabolic alterations following SARS-CoV-2 infection, 2025, Lage, Deeks, Henrich, Peluso+

    Persistent immune dysregulation and metabolic alterations following SARS-CoV-2 infection Silvia Lucena Lage; Katherine Bricker-Holt; Joseph M. Rocco; Adam Rupert; Frank X. Donovan; Yevgeniya A. Abramzon; Settara C. Chandrasekharappa; Colton McNinch; Logan Cook; Eduardo Pinheiro Amaral; Gabriel...
    • SNT Gatchaman
    • Thread
    • arachidonic acid immunometabolic inflammasome monocytes niaid nih t cells transcriptomics tryptophan
    • Replies: 6
    • Forum: Long Covid research
  6. SNT Gatchaman

    Diminished vasculogenesis under inflammatory conditions is mediated by Activin A, 2023, Manohar-Sindhu et al.

    Diminished vasculogenesis under inflammatory conditions is mediated by Activin A Manohar-Sindhu, Sahana; Merfeld-Clauss, Stephanie; Goddard, Yana; March, Keith L.; Traktuev, Dmitry O. Severe inflammatory stress often leads to vessel rarefaction and fibrosis, resulting in limited tissue...
  7. SNT Gatchaman

    A promiscuous inflammasome sparks replication of a common tumor virus, 2020, Burton et al

    A promiscuous inflammasome sparks replication of a common tumor virus Eric M. Burton, Raphaela Goldbach-Mansky, Sumita Bhaduri-McIntosh Viruses activate inflammasomes but then subvert resulting inflammatory responses to avoid elimination. We asked whether viruses could instead use such...
  8. Andy

    Review: Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response, 2019, Mohanty et al

    Paywalled at https://link.springer.com/article/10.1007%2Fs12079-019-00507-9 Sci Hub link, https://sci-hub.tw/https://link.springer.com/article/10.1007%2Fs12079-019-00507-9
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