Abstract:
The ability of cells to maintain distinct identities and respond to transient environmental signals requires tightly controlled regulation of gene networks1,2,3. These dynamic regulatory circuits that respond to extracellular cues in primary human cells remain poorly defined.
The...
Immunomodulation by endothelial cells — partnering up with the immune system?
Jacob Amersfoort, Guy Eelen and Peter Carmeliet
Blood vessel endothelial cells (ECs) have long been known to modulate inflammation by regulating immune cell trafficking, activation status and function. However...
Stratification of hospitalized COVID-19 patients into clinical severity progression groups by immuno-phenotyping and machine learning
Yvonne M. Mueller, Thijs J. Schrama, Rik Ruijten, Marco W. J. Schreurs, Dwin G. B. Grashof, Harmen J. G. van de Werken, Giovanna Jona Lasinio, Daniel...
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