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  1. Nightsong

    Preprint A Proposed Mechanism for ME/CFS Invoking Macrophage Fc-gamma-RI and Interferon Gamma, 2025, Edwards, Cambridge and Cliff

    Abstract: Evidence bearing on possible mechanisms for the clinical syndrome of ME/CFS is reviewed. The evidence is used to argue for a hypothesis that centres on a form of persistent, inappropriate, ‘neuroimmune hypervigilance’ mediated primarily by T lymphocyte-macrophage interaction but...
    • Nightsong
    • Thread
    • cd64 fcγri igg iggr interferon interferon gamma jackie cliff jo cambridge jonathan edwards t cells
    • Replies: 500
    • Forum: ME/CFS research
  2. SNT Gatchaman

    Postacute COVID-19 syndrome & fibromyalgia syndrome are associated with anti-satellite glial [IgG] but only [FM] IgG is pronociceptive, 2025, Berwick+

    Postacute COVID-19 syndrome and fibromyalgia syndrome are associated with anti-satellite glial cell IgG serum autoantibodies but only fibromyalgia syndrome serum-IgG is pronociceptive Berwick, Richard J.; Sahbaie, Peyman; Kenny, Grace; Guo, Tian-Zhi; Neiland, Harvey; Andersson, David A.; Clark...
  3. SNT Gatchaman

    SARS-CoV-2 S1 protein induces IgG-mediated platelet activation and is prevented by 1.8-cineole, 2025, Petry et al.

    SARS-CoV-2 S1 protein induces IgG-mediated platelet activation and is prevented by 1.8-cineole Petry; Shoykhet; Weiser; Griesbaum; Bashiri Dezfouli; Verschoor; Wollenberg COVID-19 patients face an increased risk of thromboembolic complications, yet the exact pathophysiological role of platelets...
  4. forestglip

    B Cell Dynamics and Transitional B Cells in Long COVID, 2025, Korobova et al

    B Cell Dynamics and Transitional B Cells in Long COVID Zoia R. Korobova, Natalia A. Arsentieva, Natalia E. Liubimova, Oleg K. Batsunov, Anastasia A. Butenko, Albina E. Kokoeva, Natalia G. Kucherenko, Victor A. Kashchenko, Ekaterina V. Boeva, Anna O. Norka, Anastasia A. Knizhnikova, Vadim V...
  5. forestglip

    Risk, determinants, and persistence of long-COVID in a population-based cohort study in Catalonia, 2025, Kogevinas et al

    Risk, determinants, and persistence of long-COVID in a population-based cohort study in Catalonia Manolis Kogevinas, Marianna Karachaliou, Ana Espinosa, Susana Iraola-Guzmán, Gemma Castaño-Vinyals, Laura Delgado-Ortiz, Xavier Farré, Natàlia Blay, Neil Pearce, Magda Bosch de Basea, Eva Alonso...
  6. forestglip

    934 – Evidence of B-Cell Dysfunction in Individuals With Long COVID-Associated Dysautonomia, 2025, Torres et al

    934 – Evidence of B-Cell Dysfunction in Individuals With Long COVID-Associated Dysautonomia Montserrat Torres, Clara Sánchez Menéndez, Alicia Simón Rueda, Ana García-Casas, Jaime Bartolomé, Luis Fernando Lemus Aguilar, Elena Mateos, Jose Aguareles, Guillermo Santamaria Corral, Aránzazu Murciano...
  7. Nightsong

    Association of high complement and low immunoglobulins with the clinical symptoms of patients with fibromyalgia, 2025, Izuno+

    Background Fibromyalgia (FM) is a disease characterized by chronic widespread pain concomitant with various symptoms such as fatigue and anxiety. Although chronic inflammation has been implicated in the immunological abnormalities of FM, there are few human studies on complement and...
  8. Nightsong

    Preprint Autoantibodies to Arginine-rich Sequences Mimicking Epstein-Barr Virus in Post-COVID and [ME/CFS], 2024, Sotzny et al

    Abstract: Background: Epstein-Barr virus (EBV) infection is a known trigger and risk factor for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and post-COVID syndrome (PCS). In previous studies, we found enhanced IgG reactivity to EBV EBNA4 and EBNA6 arginine-rich sequences in...
    • Nightsong
    • Thread
    • adra ebna4 ebna6 ebv igg long covid me/cfs scheibenbogen sepulveda slc24a3 srrm3 tgf-beta tgf-β tspyl2 tspyl5
    • Replies: 3
    • Forum: ME/CFS research
  9. SNT Gatchaman

    High Somatization Rates, Frequent Spontaneous Recovery, and a Lack of Organic Biomarkers in Post-Covid-19 Condition, 2024, Tröscher et al.

    High Somatization Rates, Frequent Spontaneous Recovery, and a Lack of Organic Biomarkers in Post-Covid-19 Condition Anna Tröscher; Patrick Gebetsroither; Marc Rindler; Vincent Böhm; Rainer Dormann; Tim von Oertzen; Anna Heidbreder; Raimund Helbok; Judith Wagner INTRODUCTION Many patients report...
  10. SNT Gatchaman

    Preprint Altered spike IgG Fc N-linked glycans are associated with hyperinflammatory state in adult COVID and [MIS-C], 2024, Sherman et al.

    Altered spike IgG Fc N-linked glycans are associated with hyperinflammatory state in adult COVID and Multisystem Inflammatory Syndrome in Children Jacob D. Sherman; Vinit Karmali; Bhoj Kumar; Trevor W. Simon; Sarah Bechnak; Anusha Panjwani; Caroline R. Ciric; Dongli Wang; Chris Huerta; Brandi...
  11. SNT Gatchaman

    Trial Report Successful Subcutaneous Immunoglobulin Therapy in a Case Series of Patients With [ME/CFS], 2024, Sjogren, Bragée, Britton.

    Successful Subcutaneous Immunoglobulin Therapy in a Case Series of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Per Sjogren; Bjorn Bragée; Sven Britton PURPOSE Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) remains an enigma with no curable treatment options at...
  12. SNT Gatchaman

    Preprint Transfer of IgG from Long COVID patients induces symptomology in mice, 2024, Vidarsson+

    Transfer of IgG from Long COVID patients induces symptomology in mice Vidarsson, G., Bos, A., van Vugt, M., den Dunnen, J., Wiersinga, W. J., Wust, R., Amsterdam UMC COVID-19 biobank,, Versteeg, S., Silva Santos Ribeiro, P., Willemen, H., Geyer, C. E., Larsen, M. D., Prado, J., Charlton, B...
  13. SNT Gatchaman

    Preprint Role of the complement system in Long COVID, 2024, Farztdinov, Scheibenbogen et al.

    Role of the complement system in Long COVID Vadim Farztdinov; Boris Zuehlke; Franziska Sotzny; Fridolin Steinbeis; Martina Seifert; Claudia Kedor; Kirsten Wittke; Pinkus Tober-Lau; Kathrin Textoris-Taube; Daniela Ludwig; Clemens Dierks; Dominik Bierbaum; Leif Erik Sander; Leif Gunnar Hanitsch...
    • SNT Gatchaman
    • Thread
    • acetylcholine bche complement igg long covid paraoxonase 3 pon3 profilin proteomics scheibenbogen study idea stxbp5 tomosyn
    • Replies: 15
    • Forum: Long Covid research
  14. SNT Gatchaman

    Sequential activation of DNA viruses by the RNA virus SARS-CoV-2 in patients with long COVID syndrome, 2023, Gyongyosi et al.

    Sequential activation of DNA viruses by the RNA virus SARS-CoV-2 in patients with long COVID syndrome Gyongyosi, M; Hasimbegovic, E; Lukovic, D; Zlabinger, K; Spannbauer, A; Samaha, E; Bergler-Klein, J; Hengstenberg, C; Mucher, P; Haslacher, H; Breuer, M; Strassl, R; Riesenhuber, M; Nitsche, C...
  15. SNT Gatchaman

    Lymph node targeted multi-epitope subunit vaccine promotes effective immunity to EBV in HLA-expressing mice, 2023, Dasari et al.

    Lymph node targeted multi-epitope subunit vaccine promotes effective immunity to EBV in HLA-expressing mice Dasari, Vijayendra; McNeil, Lisa K.; Beckett, Kirrilee; Solomon, Matthew; Ambalathingal, George; Thuy, T. Le; Panikkar, Archana; Smith, Caitlyn; Steinbuck, Martin P.; Jakubowski, Aniela...
  16. John Mac

    Investigating antibody reactivity to the intestinal microbiome in severe myalgic encephalomyelitis/chronic fatigue syndrome 2023 Carding et al

    Full title: Investigating antibody reactivity to the intestinal microbiome in severe myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) Preprint Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a multisystemic disease of unknown aetiology that is characterised...
    • John Mac
    • Thread
    • antibody carding igg immune dysfunction intestinal microbiome microbiome severe me
    • Replies: 3
    • Forum: ME/CFS research
  17. SNT Gatchaman

    Memory SARS-CoV-2 T-cell response in convalescent COVID-19 patients with undetectable specific IgG antibodies: a comparative study, 2023

    Memory SARS-CoV-2 T-cell response in convalescent COVID-19 patients with undetectable specific IgG antibodies: a comparative study Fernández-Moreno, Raquel; Valle-Arroyo, Jorge; Páez-Vega, Aurora; Salinas, Ana; Cano, Angela; Pérez, Ana B.; Torre-Cisneros, Julián; Cantisán, Sara Background...
  18. LarsSG

    Revisiting IgG antibody reactivity to Epstein-Barr virus in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome..., 2022, Sepúlveda et al

    Revisiting IgG antibody reactivity to Epstein-Barr virus in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and its potential application to disease diagnosis Abstract: Infections by the Epstein-Barr virus (EBV) are often at the disease onset of patients suffering from Myalgic...
  19. ME/CFS Skeptic

    Medscape: FDA Approves New Myasthenia Gravis Drug

    The US Food and Drug Administration (FDA) has approved efgartigimod (Vyvgart, argenx), a first-in-class, targeted therapy for adults with generalized myasthenia gravis (gMG) who test positive for the antiacetylcholine receptor (AChR) antibody... Full text at...
  20. S

    Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in SLE, 2021, Tokuyama et al

    Antibodies against human endogenous retrovirus K102 envelope activate neutrophils in systemic lupus erythematosus Maria Tokuyama, Bronwyn M. Gunn, Arvind Venkataraman, Yong Kong, Insoo Kang, Tasfia Rakib, Michael J. Townsend, Karen H. Costenbader, Galit Alter and Akiko Iwasaki Journal of...
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