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IFNγ causes mitochondrial dysfunction and oxidative stress in myositis Catalina Abad, Iago Pinal-Fernandez, Clement Guillou, Gwladys Bourdenet, Laurent Drouot, Pascal Cosette, Margherita Giannini, Lea Debrut, Laetitia Jean, Sophie Bernard, Damien Genty, Rachid Zoubairi, Isabelle Remy-Jouet...

Multi-layered deep immune profiling, SARS-CoV-2 RNAemia and inflammation in unvaccinated COVID-19 individuals with persistent symptoms Roberta Rovito, Valeria Bono, Nicolò Coianiz, Valentina Cazzetta, Sara Franzese, Joanna Mikulak, Clara Di Vito, Francesca Bai, Guillaume Beaudoin-Bussières...

Cytokine signature associated with disease severity in chronic fatigue syndrome patients Jose G Montoya, Tyson H Holmes, Jill N Anderson, Holden T Maecker, Yael Rosenberg-Hasson, Ian J Valencia, Lily Chu, Jarred W Younger, Cristina M Tato, Mark M Davis Published: July 31, 2017 [Line breaks...

Towards precision medicine for (long) COVID Perspectives on pharmacotherapy and molecular mechanisms N. Baalbaki [Line breaks added] Abstract This thesis shed light on the complex and heterogeneous nature of (long) COVID. It contributed to the characterization of both acute COVID-19 and long...

Symptoms and Pathophysiology of Post-Acute Sequelae of SARS-CoV-2 (PASC): A Cohort Study Olivier Robineau, Sophie Hüe, Mathieu Surenaud, Cédric Lemogne, Céline Dorival, Emmanuel Wiernik, Sebastian Brami, Jerome Nicol, Xavier de Lamballerie, Hélène Blanché, Jean-François Deleuze, Céline Ribet...

Exploring the landscape of symptom-specific inflammatory cytokines in post-COVID syndrome patients Chafik Tilikete, Imen Zamali, Zeineb Meddeb, Ghassen Kharroubi, Soumaya Marzouki, Tarak Dhaouadi, Ahlem Ben Hmid, Samar Samoud, Yousr Galai, Selma Charfeddine, Leila Abid, Salem Abdessalem, Jihène...

Transfer of IgG from Long COVID patients induces symptomology in mice Vidarsson, G., Bos, A., van Vugt, M., den Dunnen, J., Wiersinga, W. J., Wust, R., Amsterdam UMC COVID-19 biobank,, Versteeg, S., Silva Santos Ribeiro, P., Willemen, H., Geyer, C. E., Larsen, M. D., Prado, J., Charlton, B...

https://www.researchsquare.com/article/rs-4374986/v1 Article Impact of inflammatory response in the acute phase of COVID-19 on predicting objective and subjective post-COVID fatigue Julie Péron Anthony Nuber-Champier Gautier Breville Philippe Voruz Isabele Jacot de Alcântara Patrice Lalive...

n=31 Improvement of immune dysregulation in individuals with long COVID at 24-months following SARS-CoV-2 infection Abstract This study investigates the humoral and cellular immune responses and health-related quality of life measures in individuals with mild to moderate long COVID (LC)...

Persistent serum protein signatures define an inflammatory subcategory of long COVID Talla, Aarthi; Vasaikar, Suhas V.; Szeto, Gregory Lee; Lemos, Maria P.; Czartoski, Julie L.; MacMillan, Hugh; Moodie, Zoe; Cohen, Kristen W.; Fleming, Lamar B.; Thomson, Zachary; Okada, Lauren; Becker, Lynne A...

Highlights • Patients hospitalized for COVID-19 display marked impairment in endothelial function, which is persistent following recovery from the acute infection. • Red blood cells (RBCs) from patients with COVID-19 impair vascular function through mechanisms involving increased arginase 1...

Full title: Co-Exposure of Cardiomyocytes to IFN-γ and TNF-α Induces Mitochondrial Dysfunction and Nitro-Oxidative Stress: Implications for the Pathogenesis of Chronic Chagas Disease Cardiomyopathy Infection by the protozoan Trypanosoma cruzi causes Chagas disease cardiomyopathy (CCC) and can...

https://www.frontiersin.org/articles/10.3389/fimmu.2021.700782/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE Expression of CCR5 and its cognate ligands have been implicated in COVID-19 pathogenesis, consequently therapeutics directed against CCR5 are being...

https://link.springer.com/article/10.1007%2Fs10096-018-3265-z Eur J Clin Microbiol Infect Dis. 2018 May 26. doi: 10.1007/s10096-018-3265-z. [Epub ahead of print] Interferon-γ and CXCL10 responses related to complaints in patients with Q fever fatigue syndrome. Raijmakers RPH1,2, Jansen AFM3,4...