ibs

Characterisation of MRGPRX2+ mast cells in irritable bowel syndrome Lisse Decraecker; María Cuende Estévez; Samuel Van Remoortel; Runze Quan; Nathalie Stakenborg; Zheng Wang; Elisabetta De Marco; Alexandre Denadai-Souza; Maria Francesca Viola; Sonia Garcia Caraballo; Stuart Brierley; Yasuhiro...

Abstract: Visceral pain disorders such as interstitial cystitis/bladder pain syndrome (IC/BPS) and irritable bowel syndrome (IBS) often manifest concurrently in the bladder and colon. Yet, the mechanistic basis of such comorbidities and the transmission of neural hypersensitivity across organ...

Pediatric Gastrointestinal Tract Outcomes During the Postacute Phase of COVID-19 Dazheng Zhang et 84 al. for the Researching COVID to Enhance Recovery (RECOVER) Initiative IMPORTANCE The profile of gastrointestinal (GI) tract outcomes associated with the postacute and chronic phases of COVID-19...

Abstract Background Crohn’s disease and irritable bowel syndrome may both cause abdominal pain and diarrhea. Irritable bowel syndrome not only is an important differential diagnosis for Crohn’s disease but also occurs in one out of three patients with Crohn’s disease in remission in parallel...

Background Chronic overlapping pain conditions (COPCs), pain-related conditions that frequently occur together, may occur in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and could impact illness severity. This study aimed to identify comorbid COPCs in patients with...

At-home test can catch cancer and IBS-causing bacteria (msn.com)

NHS Talking Therapies Glaring Failures, Are Highlighted By A Focus On One of The Long-Term Conditions It Targets - CBT Watch see threads on 'mahana therapeutics', and Trial By Error: CBT and Irritable Bowel Syndrome | Science for ME (s4me.info) @dave30th

Objective: Comorbidities between internalizing disorders (IDs) and functional disorders (FDs) are well-documented, indicating shared pathways. However, their symptom-level relationships have been largely unexplored. This exploratory study employs a network approach to investigate symptoms of...

Identification of SARS-CoV-2 Persistent Infectious Epithelial Syndrome (SPIES) as a Novel Disease Entity using Clinical, Histologic, and RNA Programmatic Data Thomas Wallach, Ahmed Soliman, John Agboola, Shagun Sharma, Lais Araujo Coelho, Meredith Pittman, Christos Chatzinakos, Sergios-Orestis...

I transformed my gut health following years of agony – after one simple test (msn.com)

(I couldn’t find a thread dedicated to IBS so making a new one). Based on my knowledge of ME I’ve always assumed IBS is some sort of disease or something where no pathology has been found yet. However when I go online the only thing I can find is “Functional Gastrointestinal Disorder” which, as...

Prevalence of Fibromyalgia and Chronic Fatigue Syndrome among Individuals with Irritable Bowel Syndrome: An Analysis of United States National Inpatient Sample Database Abstract: Background and Aim: Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder associated with other...

Forgive me if I'm missing other related threads that address this issue; I'm in a bad crash and trying to write this before heading to bed--have a follow-up with my gastroenterologist tomorrow and don't want to be completely inarticulate. I've had GI issues well before I developed ME (assuming...

Free fulltext: https://genomemedicine.biomedcentral.com/articles/10.1186/s13073-023-01212-4 Research Open Access Published: 01 August 2023 Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis Markos Tesfaye...

Abstract Background Growing evidence has suggested that gut microbiota is closely related to the risk of irritable bowel syndrome (IBS), but whether there is a causal effect remains unknown. We adopted a Mendelian randomization (MR) approach to evaluate the potential causal relationships...

Background: A low-FODMAP diet is often recommended in the treatment of irritable bowel syndrome, but it does not improve abdominal symptoms in all patients, and an alternative diet is desirable. The purpose of this study was to evaluate the efficacy of a low-FODMAP diet with a concomitant...

The effect of melatonin on irritable bowel syndrome patients with and without sleep disorders: a randomized double-blinded placebo-controlled trial study 2023 Dinevari et al Abstract Background Irritable bowel syndrome (IBS) is one of the world's most common gastrointestinal (GI) disorders, and...

eta: obviously not a recommendation.

Abstract The pathogenesis of irritable bowel syndrome (IBS)—a disorder of gut-brain interaction that affects up to 10% of the world's population—remains uncertain. It is puzzling that a disorder so prevalent and archetypal among humans can be explained by disparate theories, respond to...

A role for bacterial histamine in abdominal pain Gut bacteria have been implicated in the genesis of chronic pain disorders; however, the underlying mechanisms remain unclear. In new work, De Palma and colleagues show that histamine, a known neuroimmune modulator, is produced by gut bacteria and...