Abstract
Context.— Chronic fatigue syndrome (CFS) is associated with a dysregulated hypothalamic–pituitary adrenal axis and hypocortisolemia.
Objective.— To evaluate the efficacy and safety of low-dose oral hydrocortisone as a treatment for CFS.
Design.— A randomized, placebo-controlled...
https://pubmed.ncbi.nlm.nih.gov/9989716/
A J Cleare 1, E Heap, G S Malhi, S Wessely, V O'Keane, J Miell
Abstract
Background: Reports of mild hypocortisolism in chronic fatigue syndrome led us to postulate that low-dose hydrocortisone therapy may be an effective treatment.
Methods: In a...
Abstract
A 42-year-old man who had suffered from severe fatigue for 5 years was diagnosed as having chronic fatigue syndrome (CFS) and fibromyalgia. Endocrinological workup using combined anterior pituitary function tests showed that the patient had adrenocorticotropin hormone (ACTH)...
Early in the summer I had a synthetic corticosteroid injection (Kenalog: Triamcinolone acetonide) for joint pain. To my surprise, I no longer experience the same lymph node pain and flu-like feeling on exertion. As a result I have an increased capacity for activity. It's been several months now...
Nature - molecular psychiatry
Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis? - Bornstein et al
Abstract
As millions of patients have been infected by SARS-CoV-2 virus a vast number of individuals complain about continuing...
Highlights
• ME/CFS is characterized by skewed B cell receptor gene usage.
• Upregulation of specific IGHV genes correlated to infection-related episodes at onset.
• Plasmablasts of ME/CFS patients upregulated interferon response genes.
• B cell receptor repertoire analysis can provide a useful...
Full title: General theory of inflammation: patient self-administration of hydrocortisone safely achieves superior control of hydrocortisone-responding disorders by matching dosage with symptom intensity
Open access at...
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