hla

  1. hotblack

    HLA imputation and its application to genetic and molecular fine-mapping of the MHC region in autoimmune diseases, 2021, Naito & Okada

    HLA imputation and its application to genetic and molecular fine-mapping of the MHC region in autoimmune diseases Tatsuhiko Naito, Yukinori Okada Abstract Variations of human leukocyte antigen (HLA) genes in the major histocompatibility complex region (MHC) significantly affect the risk of...
  2. hotblack

    Efficient HLA imputation from sequential SNPs data by transformer, 2023, Tanaka et al

    Efficient HLA imputation from sequential SNPs data by transformer Kaho Tanaka, Kosuke Kato, Naoki Nonaka & Jun Seita Abstract Human leukocyte antigen (HLA) genes are associated with a variety of diseases, yet the direct typing of HLA alleles is both time-consuming and costly. Consequently...
  3. hotblack

    Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease, 2023, Sakaue et al

    Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease. Saori Sakaue, Saisriram Gurajala, Michelle Curtis, Yang Luo, Wanson Choi, Kazuyoshi Ishigaki, Joyce B. Kang, Laurie Rumker, Aaron J. Deutsch, Sebastian Schönherr, Lukas Forer, Jonathon LeFaive, Christian...
  4. hotblack

    The UK Biobank resource with deep phenotyping and genomic data, 2018, Bycroft et al

    The UK Biobank resource with deep phenotyping and genomic data Clare Bycroft, Colin Freeman, Desislava Petkova, Gavin Band, Lloyd T. Elliott, Kevin Sharp, Allan Motyer, Damjan Vukcevic, Olivier Delaneau, Jared O’Connell, Adrian Cortes, Samantha Welsh, Alan Young, Mark Effingham, Gil McVean...
  5. SNT Gatchaman

    Preprint Dissecting the genetic complexity of myalgic encephalomyelitis/chronic fatigue syndrome via deep learning-powered genome analysis, 2025, Zhang+

    Dissecting the genetic complexity of myalgic encephalomyelitis/chronic fatigue syndrome via deep learning-powered genome analysis Sai Zhang; Fereshteh Jahanbani; Varuna Chander; Martin Kjellberg; Menghui Liu; Katherine Glass; David Iu; Faraz Ahmed; Han Li; Rajan Douglas Maynard; Tristan Chou...
    • SNT Gatchaman
    • Thread
    • b cells cd4+ genetics hanson hla machine learning neuroligin proteasome t cells ubiquitin
    • Replies: 440
    • Forum: ME/CFS research
  6. forestglip

    HLA-A*03 may confer protection against long COVID through an enhanced immune response, 2025, Pons-Fuster et al

    HLA-A*03 may confer protection against long COVID through an enhanced immune response Eduardo Pons-Fuster, Rodrigo Martinez-Rodriguez, Lourdes Gimeno-Arias, M.J. Alcaraz, Marta Moreno, Jose M. Gómez, Ana Pelaez, Elisa García, Cristina Tomás, Angeles Muñoz, María V. Martínez-Sánchez, Inmaculada...
    • forestglip
    • Thread
    • cd8+ hla hla-a*03 kir kir2dl1 kir3dl1 long covid nk cells risk factors tigit
    • Replies: 8
    • Forum: Long Covid research
  7. forestglip

    Negative Association of [GWI] Symptomatology with Predicted Binding Affinity of Anthrax Vaccine Antigen to [HLA II molecules], 2025, James et al

    Negative Association of Gulf War Illness Symptomatology with Predicted Binding Affinity of Anthrax Vaccine Antigen to Human Leukocyte (HLA) Class II Molecules Lisa M James, Apostolos P Georgopoulos Background Anthrax is a serious disease caused by Bacillus anthracis (B. anthracis) with a very...
  8. forestglip

    Opinion Human Leukocyte Antigen (HLA) at the Root of Persistent Antigens and Long COVID, 2025, Georgopoulos et al

    Human Leukocyte Antigen (HLA) at the Root of Persistent Antigens and Long COVID Apostolos P. Georgopoulos, Lisa M. James, Phillip K. Peterson (Line break added) Abstract Here we offer a perspective on recent findings of persistent SARS-CoV-2 antigens in Long COVID through the lens of...
  9. SNT Gatchaman

    HLA-DQB1*05:03 is associated with an increased risk of COVID-19 progression in the Bulgarian population, 2025, Lukanov et al.

    HLA-DQB1*05:03 is associated with an increased risk of COVID-19 progression in the Bulgarian population Lukanov; Mihaylova; Al Hadra; Lesichkova; Georgieva; Popov; Krasteva; Mondeshki; Naumova The SARS‐CoV‐2 outbreak represents a global health problem. The different infection rates are heavily...
  10. SNT Gatchaman

    Influence of HLA-G 3′ Untranslated Region Haplotypes and SNP +3422 Gene Variants […] During Acute and Post-Acute Phases […], 2024, Rohn+

    Influence of HLA-G 3′ Untranslated Region Haplotypes and SNP +3422 Gene Variants as Host Genetic Factors on the Outcomes of SARS-CoV-2 Infection During Acute and Post-Acute Phases in a German Cohort Hana Rohn; Fynn Elischer; Louisa Larbig; Sarah Jansen; Sabine Schramm; Mona Otte; Margarethe...
  11. SNT Gatchaman

    Immune exhaustion in ME/CFS and long COVID, 2024, Eaton-Fitch et al.

    Immune exhaustion in ME/CFS and long COVID Natalie Eaton-Fitch; Penny Rudd; Teagan Er; Livia Hool; Lara Herrero; Sonya Marshall-Gradisnik Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and long COVID are debilitating multisystemic conditions sharing similarities in immune...
    • SNT Gatchaman
    • Thread
    • eaton-fitch hla hla-dqb1 ighg immune dysregulation innate immune system interferon kir marshall-gradisnik ncned
    • Replies: 12
    • Forum: ME/CFS research
  12. forestglip

    Autoantibodies, Polymorphisms in the Serotonin Pathway, and Human Leukocyte Antigen Class II Alleles in [CFS], 2009, Ortega-Hernandez et al

    Autoantibodies, Polymorphisms in the Serotonin Pathway, and Human Leukocyte Antigen Class II Alleles in Chronic Fatigue Syndrome Oscar-Danilo Ortega-Hernandez, Mariaclara Cuccia, Sara Bozzini, Nicola Bassi, Samuel Moscavitch, Lina-Marcela Diaz-Gallo, Miri Blank, Nancy Agmon-Levin, Yehuda...
    • forestglip
    • Thread
    • age of onset antineuronal cell antibodies arthralgia autoantibodies fever hla me/cfs myalgia serotonin serotonin receptor-2a gene serotonin transporter gene
    • Replies: 0
    • Forum: ME/CFS research
  13. forestglip

    Molecular study of receptor for [AGE] gene promoter and identification of specific HLA haplotypes possibly involved in [CFS], 2009, Carlo-Stella et al

    Molecular study of receptor for advanced glycation endproduct gene promoter and identification of specific HLA haplotypes possibly involved in chronic fatigue syndrome N Carlo-Stella, S Bozzini, A De Silvestri, I Sbarsi, C Pizzochero, L Lorusso, M Martinetti, M Cuccia Abstract The receptor...
  14. Wyva

    Immunometabolic changes and potential biomarkers in CFS peripheral immune cells revealed by single-cell RNA sequencing, 2024, Sun et al

    Abstract The pathogenesis of Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) remains unclear, though increasing evidence suggests inflammatory processes play key roles. In this study, single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) was used to...
    • Wyva
    • Thread
    • 2024 amyloid amyloid precursor protein biomarker cd74 china cytoskeleton esrra hla hla-dqb1 immune dysregulation immunometabolism integrated stress response nk cells oestrogen pbmc resistin single-cell rna-sequencing t cells
    • Replies: 26
    • Forum: ME/CFS research
  15. Nightsong

    Multi-ancestry GWAS of [LC] identifies immune-related loci and etiological links to [CFS], fibromyalgia and depression, 2024, Chaudhary et al

    Multi-ancestry GWAS of Long COVID identifies‬ ‭immune-related loci and etiological links to chronic fatigue‬ syndrome, fibromyalgia and depression‬ ‭ Abstract The etiology of Long COVID is poorly understood despite its estimated global burden of 65 million cases. There exists a paucity of...
  16. SNT Gatchaman

    SARS-CoV-2-specific CD8+ T cells from people with [LC] establish and maintain effector phenotype and key TCR signatures over 2 years, 2024, Rowntree+

    SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years Rowntree, Louise C.; Audsley, Jennifer; Allen, Lilith F.; McQuilten, Hayley A.; Hagen, Ruth R.; Chaurasia, Priyanka; Petersen, Jan; Littler, Dene R.; Tan...
  17. SNT Gatchaman

    Persistence of circulating CD169+monocytes and HLA-DR downregulation underline the immune response impairment in PASC, 2024, Fanelli et al.

    Persistence of circulating CD169+monocytes and HLA-DR downregulation underline the immune response impairment in PASC individuals: the potential contribution of different COVID-19 pandemic waves Fanelli; Petrone; Maracchioni; Chirico; Cipriani; Coppola; Malagnino; Teti; Sorace; Zordan; Vitale...
  18. Midnattsol

    Hypothesis Ineffective control of Epstein-Barr-virus-induced autoimmunity increases the risk for multiple sclerosis, 2023, Vietzen et al.

    I wasn't sure what prefix to use given that the paper has been accepted in Cell but not published. I read about it in a paywalled news article as the abstract was presented at the ECTRIMS 2023. Ineffective Immune Control of Epstein-Barr Virus-Induced Autoreactive Responses is an Important Cause...
  19. Dolphin

    Immune cell proteomes of Long COVID patients have functional changes similar to those in ME/Chronic Fatigue Syndrome, 2023, Peppercorn, Tate et al.

    https://www.researchsquare.com/article/rs-3335919/v1 Article Immune cell proteomes of Long COVID patients have functional changes similar to those in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Katie Peppercorn1 Christina D. Edgar1 Torsten Kleffmann1 Warren. P Tate1 Email 1...
    • Dolphin
    • Thread
    • hla hla-dqb1 lc=me/cfs new zealand peroxiredoxin proteomics warren tate
    • Replies: 11
    • Forum: ME/CFS research
  20. E

    Review Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID?, 2023, Ruiz-Pablos et al

    Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID? Abstract Both myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) and long COVID (LC) are characterized by similar immunological alterations, persistence of chronic viral infection...
    • EndME
    • Thread
    • autoimmune disease ebv epstein-barr hla immunodeficiency long covid me/cfs mecfs ruiz-pablos treatment virus
    • Replies: 19
    • Forum: Long Covid research
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