gamma-delta t cells

  1. Nightsong

    Killer cell immunoglobulin-like receptor (KIR) alleles suggested to be associated with [ME/CFS], 2025, Ramadan et al

    Abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic and debilitating disease with unknown cause. Involvement of infection and immune dysregulation has been suggested, including changes in immune cell subsets and abnormal functions of natural killer (NK) cells. The...
    • Nightsong
    • Thread
    • cmv ebv fluge gamma-delta t cells hla innate immune system kir me/cfs mella nk cells
    • Replies: 6
    • Forum: ME/CFS research
  2. Hutan

    Genetics: BTN2A2 and BTN3A3

    DecodeME candidate ME/CFS gene CHROMOSOME 6p Chr6p contained seven Tier 1 genes. *************************** BTN2A2 (Tier 1) • Protein: Butyrophilin subfamily 2 member A2. UniProt. GeneCards. The allele that increases the risk of ME/CFS is associated with decreasing BTN2A2 gene expression...
  3. SNT Gatchaman

    Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children MIS-C, 2024, Bellos et al.

    Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children MIS-C Bellos, Evangelos and 97 others Multisystem inflammatory syndrome in children (MIS-C) is a rare condition following SARS-CoV-2 infection associated with intestinal manifestations. Genetic...
    • SNT Gatchaman
    • Thread
    • butyrophylin gamma-delta t cells gastrointestinal genetic polymorphisms gut barrier gut permeability mis-c
    • Replies: 1
    • Forum: Long Covid research
  4. Andy

    Butyrophilin-like 3 Directly Binds a Human Vγ4+ T Cell Receptor Using a Modality Distinct from Clonally-Restricted Antigen 2019 Wilcox et al

    Highlights BTNL3 binds directly and specifically to Vγ4+ TCRs via its IgV domain The superantigen-like binding mode focuses on germline-encoded TCR regions In contrast, γδ TCR binding to a clonally restricted antigen is CDR3-mediated Mutagenesis indicates parallels with BTN3A1-mediated...
  5. pooriepoor91

    AI-driven multi-omics modeling of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, 2025, Xiong et al.

    Now published - see post #20 Ruoyun Xiong, Elizabeth Aiken, Ryan Caldwell, Suzanne D. Vernon, Lina Kozhaya, Courtney Gunter, Lucinda Bateman, Derya Unutmaz & Julia Oh ******************************** https://www.biorxiv.org/content/10.1101/2024.06.24.600378v1 BioMapAI: Artificial Intelligence...
    • pooriepoor91
    • Thread
    • artificial intelligence bile acid biomapai gamma-delta t cells interferon interferon gamma lipids mait cells multi-omics unutmaz vernon
    • Replies: 43
    • Forum: ME/CFS research
  6. SNT Gatchaman

    Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations, 2023, Habel et al.

    Immune profiling of SARS-CoV-2 infection during pregnancy reveals NK cell and γδ T cell perturbations Jennifer R. Habel; Brendon Y. Chua; Lukasz Kedzierski; Kevin J. Selva; Timon Damelang; Ebene R. Haycroft; Thi H.O. Nguyen; Hui-Fern Koay; Suellen Nicholson; Hayley A. McQuilten; Xiaoxiao Jia...
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