exercise physiology

  1. Dolphin

    Exercise Pathophysiology in ME/CFS and Long COVID: Commonalities Detected by Invasive Cardiopulmonary Exercise Testing, 2025, Squires, Systrom et al

    https://www.atsjournals.org/doi/abs/10.1164/ajrccm.2025.211.Abstracts.A7881 Exercise Pathophysiology in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Long COVID: Commonalities Detected by Invasive Cardiopulmonary Exercise Testing J. Squires 1, S. Palwayi 1, P. Li 3, W. Xiao 3, K...
  2. SNT Gatchaman

    The effect of COVID-19 on cardiovascular function and exercise tolerance in healthy middle-age and older individuals, 2025, Russell+

    The effect of COVID-19 on cardiovascular function and exercise tolerance in healthy middle-age and older individuals Sophie L. Russell; Nduka C. Okwose; Mushidur Rahman; Ben J Lee; Gordon McGregor; Stuart M. Raleigh; Hardip Sandhu; Laura C. Roden; Prithwish Banerjee; Djordje G. Jakovljevic AIMS...
  3. Trish

    Is PEM triggered by physical exertion the same as worsening triggered by sensory stimuli, cognitive exertion or emotions? What are the implications?

    I have started this thread in order to reduce diversion of another thread where the subject arose. Here are a couple of quotes from that thread: My questions for discussion: pwME experiences: Is the worsening of symptoms triggered by sensory stimuli such as light and sound the same from a...
  4. Andy

    Comparison of the muscle oxygenation during submaximal and maximal exercise tests in patients post-[COVID-19]... 2024 Başak Kavalcı Kol et al

    Full title: Comparison of the muscle oxygenation during submaximal and maximal exercise tests in patients post-coronavirus disease 2019 syndrome with pulmonary involvement ABSTRACT Introduction Pulmonary involvement is prevalent in patients with coronavirus disease 2019 (COVID-19). Arterial...
  5. E

    Mechanisms underlying exercise intolerance in Long COVID: an accumulation of multi-system dysfunction, 2023, Jamieson et al

    Now published - final abstract here Preprint Mechanisms underlying exercise intolerance in Long COVID: an accumulation of multi-system dysfunction The pathogenesis of exercise intolerance and persistent fatigue which can follow an infection with the SARS-CoV-2 virus ('Long COVID') is not fully...
  6. Dolphin

    Trial Report Exercise capacity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) treated with long-term pyridostigmine, 2023, Systrom

    https://erj.ersjournals.com/content/62/suppl_67/PA4639 Exercise capacity in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) treated with long-term pyridostigmine Johanna Squires, Sarra Al-Zayer, David Systrom European Respiratory Journal 2023 62: PA4639; DOI...
  7. E

    Utility of 2-day Cardiopulmonary Exercise Testing Protocol in LONG-HAUL COVID (LHC) PATIENTS: PRELIMINARY DATA, 2023, Abbasi et al

    UTILITY OF 2-DAY CARDIOPULMONARY EXERCISE TESTING PROTOCOL IN LONG-HAUL COVID (LHC) PATIENTS: PRELIMINARY DATA Purpose: Long Haul COVID (LHC) patients have prominent symptoms of fatigue and exercise limitation. Comparisons have been made between Chronic Fatigue Syndrome/Myalgic...
  8. Hutan

    Muscle oxygenation [as assessed by NIRS - Near Infra-Red Spectroscopy]

    This study found reduced oxygen extraction in the thigh muscles of people with ongoing symptoms after Covid-19 infections as compared to healthy controls: Structural and functional impairments of skeletal muscle in patients with [PASC], 2023, Colosio et al. The measure is "Δ[HHbMb]peak (%...
  9. SNT Gatchaman

    Decreased physical performance despite objective and subjective maximal exhaustion in post-COVID-19 individuals with fatigue, 2023, Vollrath et al.

    Decreased physical performance despite objective and subjective maximal exhaustion in post-COVID-19 individuals with fatigue Vollrath, Shirin; Matits, Lynn; Schellenberg, Jana; Kirsten, Johannes; Steinacker, Jürgen M.; Bizjak, Daniel A. Introduction Fatigue is a common symptom in post-COVID-19...
  10. Andy

    Cardiopulmonary Profiling of Athletes with Post-Exertional Malaise after COVID-19 Infection—A Single-Center Experience, 2023, Wernhart et al

    Abstract Background: Cardiopulmonary exercise testing (CPET) has been suggested by the European Society of Cardiology (ESC) for assessing the exercise limitations of apparently healthy individuals, but data on elite athletes regarding this test are scarce. Methods: We analyzed CPET in elite...
  11. Trish

    The Intriguing Role of Histamine in Exercise Responses, 2017, Luttrell

    The Intriguing Role of Histamine in Exercise Responses 2017 Luttrell and Halliwill Brief Abstract In humans, histamine is a molecular transducer of physical activity responses, and antihistamines modify more than 25% of the genes responding to exercise. Although the upstream signal that results...
  12. Andy

    Cardiac output and arteriovenous oxygen difference contribute to lower peak oxygen uptake in patients with fibromyalgia, 2023, Lehto et al

    Background Patients with fibromyalgia (FM) exhibit low peak oxygen uptake ( ˙VO2peak). We aimed to detect the contribution of cardiac output to ( ˙Q) and arteriovenous oxygen difference [C(a-v)O2] to ˙VO2 from rest to peak exercise in patients with FM. Methods Thirty-five women with FM, aged...
  13. SNT Gatchaman

    Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired [CPET] in [PASC], 2023, Singh et al.

    Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS-CoV-2 infection (PASC) syndrome Inderjit Singh; Brooks P. Leitner; Yiwei Wang; Hanming Zhang; Phillip Joseph; Denyse...
  14. Andy

    Altered muscle oxidative phenotype impairs exercise tolerance but does not improve after exercise training in multiple sclerosis, 2022, Spaas et al

    Abstract Background Patients with multiple sclerosis (MS) experience reduced exercise tolerance that substantially reduces quality of life. The mechanisms underpinning exercise intolerance in MS are not fully clear. This study aimed to determine the contributions of the cardiopulmonary system...
  15. Mij

    Use of Cardiopulmonary Exercise Testing to Evaluate Long COVID-19 Symptoms in Adults - A Systematic Review and Meta-analysis, 2022, Durstenfeld et al

    Preprint Abstract Importance: Reduced exercise capacity is commonly reported among individuals with Long COVID (LC). Cardiopulmonary exercise testing (CPET) is the gold-standard to measure exercise capacity to identify causes of exertional intolerance. Objectives: To estimate the effect of...
  16. Andy

    Reduced exercise capacity, chronotropic incompetence, early systematic inflammation in cardiopulmonary phenotype Long COVID, 2023, Durstenfeld et al

    Preprint. Inflammation during early post-acute COVID-19 is associated with reduced exercise capacity and Long COVID symptoms after 1 year, 2022, Durstenfeld Abstract BACKGROUND Mechanisms underlying persistent cardiopulmonary symptoms following SARS-CoV-2 infection (post-acute sequelae of...
  17. Andy

    Predictors of Submaximal Exercise Test Attainment in Adults Reporting Long COVID Symptoms, 2022, Romero-Ortuno et al

    Abstract Adults with long COVID often report intolerance to exercise. Cardiopulmonary exercise testing (CPET) has been used in many settings to measure exercise ability but has been conducted in a few long COVID cohorts. We conducted CPET in a sample of adults reporting long COVID symptoms...
  18. Sly Saint

    Neurovascular Dysregulation and Acute Exercise Intolerance in ME/CFS: A Randomized, Placebo-Controlled Trial of Pyridostigmine, 2022, Systrom et al

    ABSTRACT Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is characterized by intractable fatigue, post-exertional malaise, and orthostatic intolerance, but its pathophysiology is poorly understood. Pharmacologic cholinergic stimulation was used to test the hypothesis that...
  19. Hutan

    Time course of exercise induced alterations in daily activity in CFS, 2005, Black and McCully

    2005 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1280928/ Abstract In a previous study we demonstrated that while people with CFS had lower daily activity levels than control subjects, they were able to increase daily activity via a daily walking program. We reanalyzed our data to determine...
  20. Andy

    Chronotropic Incompetence in Non-Hospitalized Patients with Post-COVID-19 Syndrome, 2021, Jimeno-Almazán et al

    Abstract Patients recovering from COVID-19 commonly report persistence of dyspnea, exertional fatigue, and difficulties in carrying out their daily activities. However, the nature of these symptoms is still unknown. The purpose of the study was to identify limiting causes of cardiopulmonary...
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