er stress

  1. SNT Gatchaman

    Review Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2025, Syed, Karius, Wang, Hwang

    Mitochondrial Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Abu Mohammad Syed; Alexander K. Karius; Jin Ma; Ping-yuan Wang; Paul M. Hwang ME/CFS is a debilitating multisystem disorder of unclear etiology that affects many individuals worldwide. One of its hallmark symptoms...
    • SNT Gatchaman
    • Thread
    • actin atp eif2a endoplasmic reticulum er stress interferon jak-stat mitochochria mitochondrial dysfunction nf-κb wasf3
    • Replies: 15
    • Forum: ME/CFS research
  2. SNT Gatchaman

    Proteolethargy is a pathogenic mechanism in chronic disease, 2024, Dall’Agnese et al

    Proteolethargy is a pathogenic mechanism in chronic disease Alessandra Dall’Agnese; Ming M. Zheng; Shannon Moreno; Jesse M. Platt; An T. Hoang; Deepti Kannan; Giuseppe Dall’Agnese; Kalon J. Overholt; Ido Sagi; Nancy M. Hannett; Hailey Erb; Olivia Corradin; Arup K. Chakraborty; Tong Ihn Lee...
    • SNT Gatchaman
    • Thread
    • chronic illness cysteine cytoplasm endoplasmic reticulum enos er stress insulin receptor insulin resistance mitochochria protein mobility proteolethargy reactive oxygen species
    • Replies: 13
    • Forum: Other health news and research
  3. pooriepoor91

    Review Assessment of the therapeutic potential of salubrinal for ME/CFS and long-COVID, 2024,Warrayat et al.

    Link: Assessment of the therapeutic potential of salubrinal for ME/CFS and long-COVID - ScienceDirect Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic debilitating condition with no cure that shares commonality with long-COVID. This review examines current...
  4. SNT Gatchaman

    Review Type I interferons and endoplasmic reticulum stress in health and disease, 2020, Sprooten and Garg

    Type I interferons and endoplasmic reticulum stress in health and disease Sprooten; Garg Type I interferons (IFNs) comprise of pro-inflammatory cytokines created, as well as sensed, by all nucleated cells with the main objective of blocking pathogens-driven infections. Owing to this broad range...
  5. SNT Gatchaman

    Review Unraveling the Connection: Pain and Endoplasmic Reticulum Stress, 2024, Kawanaka et al.

    Unraveling the Connection: Pain and Endoplasmic Reticulum Stress Kawanaka, Ryoko; Jin, Hisayo; Aoe, Tomohiko Pain is a complex and multifaceted experience. Recent research has increasingly focused on the role of endoplasmic reticulum (ER) stress in the induction and modulation of pain. The ER...
  6. SNT Gatchaman

    Assessing the effect of selective serotonin reuptake inhibitors in the prevention of post-acute sequelae of COVID-19, 2024, Sidky et al.

    Assessing the effect of selective serotonin reuptake inhibitors in the prevention of post-acute sequelae of COVID-19 Hythem Sidky; Kristen A. Hansen; Andrew T. Girvin; Nathan Hotaling; Sam G. Michael; Ken Gersing; David K. Sahner BACKGROUND Post-acute sequelae of COVID-19 (PASC) produce...
  7. SNT Gatchaman

    Review Sphingolipids and their metabolism in physiology and disease, 2017, Hannun, Yusuf A. and Obeid, Lina M.

    Sphingolipids and their metabolism in physiology and disease Hannun, Yusuf A.; Obeid, Lina M. Studies of bioactive lipids in general and sphingolipids in particular have intensified over the past several years, revealing an unprecedented and unanticipated complexity of the lipidome and its many...
    • SNT Gatchaman
    • Thread
    • ceramide endoplasmic reticulum er stress golgi histone lipid droplets lipid metabolism lipid rafts lipids s1pr sphingolipids sphingomyelin upr
    • Replies: 5
    • Forum: Other health news and research
  8. SNT Gatchaman

    Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture, 2023, Davies et al.

    Expression of SARS-CoV-2 Nonstructural Proteins 3 and 4 Can Tune the Unfolded Protein Response in Cell Culture Jonathan P. Davies; Athira Sivadas; Katherine R. Keller; Brynn K. Roman; Richard J.H. Wojcikiewicz; Lars Plate Coronaviruses (CoV), including SARS-CoV-2, modulate host proteostasis...
  9. SNT Gatchaman

    Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle, 2022, McNally et al.

    Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle McNally, Ben D.; Ashley, Dean F.; Hänschke, Lea; Daou, Hélène N.; Watt, Nicole T.; Murfitt, Steven A.; MacCannell, Amanda D. V.; Whitehead, Anna; Bowen, T. Scott; Sanders...
  10. SNT Gatchaman

    Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response, 2016, Kim et al.

    Lipid Biosynthesis Coordinates a Mitochondrial-to-Cytosolic Stress Response Hyun-Eui Kim; Ana Rodrigues Grant; Milos S. Simic; Rebecca A. Kohnz; Daniel K. Nomura; Jenni Durieux; Celine E. Riera; Melissa Sanchez; Erik Kapernick; Suzanne Wolff; Andrew Dillin Summary Defects in mitochondrial...
  11. SNT Gatchaman

    Preprint Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis, 2023, Li et al.

    Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis Jeson J Li; Nan Xin; Chunxia Yang; Larrisa A Tavizon; Ruth Hong; Travis I Moore; Rebecca G Tharyan; Adam Antebi; Hyun-Eui Kim Maintaining protein homeostasis is essential...
  12. SNT Gatchaman

    Endoplasmic Reticulum ER Stress Response Failure in Diseases, 2020, Bhattarai et al.

    Endoplasmic Reticulum ER Stress Response Failure in Diseases Kashi Raj Bhattarai; Manoj Chaudhary; Hyung-Ryong Kim; Han-Jung Chae Recent work provides evidence for the new terminology, ‘endoplasmic reticulum (ER) stress response or sensing failure’, in relation to metabolic disease. We seek to...
  13. SNT Gatchaman

    The Role of the Hypoxia-Related Unfolded Protein Response UPR in the Tumor Microenvironment, 2022, Bartoszewska et al.

    The Role of the Hypoxia-Related Unfolded Protein Response UPR in the Tumor Microenvironment Bartoszewska, Sylwia; Collawn, James F.; Bartoszewski, Rafal Despite our understanding of the unfolded protein response (UPR) pathways, the crosstalk between the UPR and the complex signaling networks...
  14. Hoopoe

    WASF3 disrupts mitochondrial respiration and may mediate exercise intolerance in myalgic encephalomyelitis/chronic fatigue syndrome, 2023 Hwang et al

    The pre-publication thread has been merged with the thread on the paper. Link to paper's abstract here...
    • Hoopoe
    • Thread
    • bip endoplasmic reticulum er stress exercise intolerance grp78 mitochondrial function mouse model muscle biopsy p53 perk salubrinal seahorse study idea wasf3 wave3
    • Replies: 246
    • Forum: ME/CFS research
  15. Hutan

    ER Stress-Sensor Proteins and ER-Mitochondrial Crosstalk—Signaling Beyond (ER) Stress Response, 2021, Kumar and Maity

    https://www.mdpi.com/2218-273X/11/2/173/htm Abstract Recent studies undoubtedly show the importance of inter organellar connections to maintain cellular homeostasis. In normal physiological conditions or in the presence of cellular and environmental stress, each organelle responds alone or in...
  16. Hoopoe

    Muscle endoplasmic reticulum stress in exercise, Marafon et al 2022

    Abstract The endoplasmic reticulum (ER) is an organelle responsible for the post-translational folding and modification of proteins. Under stress conditions, such as physical exercise, there is accumulation of misfolded proteins. The increased load of proteins in the ER results in ER stress...
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